About
The Laboratory of Bioorganic Compound Chemistry is a non-academic unit of the Institute of Biochemistry. Since its establishment, the laboratory has been working in the experimental site located at 12 Mokslininkų Street. In addition to the laboratory facilities, it has an organic synthesis workshop and an autoclave - a separate unit adapted for high-pressure synthesis work.
The Bioorganic Compounds Chemistry Laboratory's research interests are: the synthesis of amino acids and their derivatives, the development of methods and technologies for the synthesis of macrocyclic and linear polyethers, and the study of the synthesis, structure, and other properties of various heterocyclic compounds. Since 2014, the main objective of the laboratory is to carry out experimental development and applied research in the field of organic chemistry, and to provide outsourced synthesis research services. This research is carried out in cooperation with Lithuanian and foreign business entities that are interested in putting the results of fundamental research into practice. Cooperation partners are Ramidus AB (Sweden), Synthon Chemicals GmbH (Germany), Polypure AS (Norway), Bapeks SIA (Latvia), UAB Thermofisher Scientific Baltics (Lithuania), UAB Elymus (Lithuania), UAB Biotecha (Lithuania),UAB Ekorama (Lithuania), UAB Sanobiotec, UAB Vilniaus Ventos Puslaidininkiai (Lithuania).
The current activities of the laboratory are linked to a key strategic direction: the laboratory is to become a link between research and production and the market, with a wide range of pilot to industrial scale production.
Our equipment, glass, enamelled, stainless steel reactors (10-1600 L) and catalytic hydrotreaters (0.2-10 L), allow us to study chemical processes in a wide range of volumes.
We offer a wide range of services in the field of organic synthesis for scientists and business:
- Development and optimisation of technologies for the synthesis of chemical compounds.
- Testing of laboratory technologies for chemical processes developed by our partners for a wide range of product volumes, from the order of grams to hundreds of kilograms.
- Investigation of synthesis methods for various classes of organic compounds, development and testing of multi-step synthesis schemes.
- Custom synthesis of a variety of chemicals for scientific and commercial applications from grams to hundreds of kilograms, depending on the structure of the compounds and the customer's requirements.
The list of compounds synthesised in the laboratory includes over 200 compounds for scientific and commercial applications:
- O,N and S-heterocyclic compounds
- Thiols, thioethers and thioamides
- Stereoisomeric derivatives of dipakey cyclohexane
- Aromatic carboxylic acids
- Amino acid derivatives
- Mono- and diphenyl substituted cyclic polyethers
- Aminonaphthalenesulfoamides
- Monodisperse derivatives of polyethylene glycols
- Enzyme cofactors
Personnel
Head
dr. Mantas Jonušis
researcher
85 272 9058
Staff
| Regina Jančienė biochemist 852729058 |
Dr. Algirdas Klimavičius biochemist 852729058 |
Jonas Meškauskas biochemist 852729058 |
Dr. Algirdas Palaima senior researcher |
| Ričardas Rozenbergas biochemist 852729058 |
Dr. Zita Staniulytė biochemist 852729058 |
Stanislava Palaikienė administrator 852729058 |
|
| Simona Jonušienė junior researcher |
Ilona Levutienė technician |
Ala Peteraitienė technician |
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| Olga Sivova technician 852729058 |
Kazimieras Vitkauskas technician |
Juozas Puzas technician |