About
Research interests
Investigation of bioelectrochemical properties of biomolecules
Investigation of electron transport in biomolecules
Creation of biosensors and bioreactors
Investigation of the mechanism of action of biomolecules and cells in heterogeneous systems and mathematical modeling.
Group of Supramolecular Analysis
RESEARCH OWEREVIEW
Specially prepared carbon materials can possess direct electrochemical communication with redox centers of some redox proteins. For this reason a few types of graphite nanoparticles have been manufactured by oxidation of graphite using different protocols and characterized by AFM, Raman spectroscopy, TGA and BET analysis. Also thermally reduced graphene oxides and nanocomposite materials have been prepared and studied. Different oxidoreductases were applied and demonstrated direct electron transport between surface of the carbon materials and active center of the enzyme. These structures were applied in different technological structures. One of them - creation of mediatorless bio-anodes and bio-cathodes for bio-solar cells, bio-batteries and bio-fuel cells.
Second direction -the same structures were applied for the creation of new type of biosensors for the determination of the sugars and alcohols. Carbon materials were applied for the electrochemical monitoring of urease activity and electrochemical biosensors for urea were developed. These biosensors were applied in medicine, environment control, and for the quality control in food industry. In this field the project „Non- invasive approach to early diagnosis and prognosis of acute severe pancreatitis (AP)” was recently funded. The ambitiousness of the project is to diminish lack of information causing AP diagnostic, prognostic and followed treatment problems by deep understanding of AP biochemical processes that could help to create new diagnostic tools. Beekeeping products conserved with honey were analyzed. Monitoring of the changes of parameters of the mixtures via different storage conditions revealed a stabilizing influence of honey and additives on anti-oxidative properties, composition of flavonoids and activity of the enzymes of the mixtures.
Third direction - the same bio-electro-catalytic system was applied in bioreactors for the selective conversion of substrates into useful products. Conversion of N-hydroxy- compounds, alcohols and other substrates catalysed by oxidoreductases (laccases, peroxidases and quinoprotein dehydrogenases) was investigated. These systems were extended into multi-step synthesis of natural products & analogues involving sequences of enzymes conversion chains.
The numerical mathematical modelling of heterogeneous bio-electro-catalytic systems made possible to determine several structural and kinetic parameters of the sensor and bioreactor construction.
Bioluminescence imaging experiments were carried out to characterize spatiotemporal patterns of self-organization of bioluminescent E. coli and its mutants in standard microtiter plates. An analysis of the effects of mutations shows that spatiotemporal patterns formed due to migration (swimming) of cells near three phase contact line are not related to the chemotaxis system of bacteria. An analysis of experimental data and mathematical modelling of pattern formation indicate that pattern-forming active bacteria can be interpreted as self-phoretic cells dispersed in a liquid suspension.
Department participated in the international sheering of the food quality control knowledge. Food safety and Food safety assessment training courses were translated into Lithuanian language and distributed among food producers. Department participated in the introduction of ES Food safety legislation into food industry system in Turkey.
Publications
2024
- Kosychova L., L. Rekovič, I. Bratkovskaja, I. Radveikienė, R. Vidžiūnaitė. 2024. Oxidation of 1,5-benzodiazepine oximes catalysed by peroxidases. Journal of the Serbian Chemical Society 89(2): 151-164.
- Ratautė K., D. Ratautas. A review from a clinical perspective: recent advances in biosensors for the detection of L-amino acids. Biosensors-Basel 14(10): 5.
- Tchekwagep P. M.S., R. Žalneravičius, C. P. Nanseu-Njiki, E. Ngameni, T. Arnebrant, T. Ruzgas. 2024. Electrochemical insights into layered assemblies of silver nanoparticles, poly-L-lysine, and bovine serum albumin. Electroanalysis DOI10.1002/elan.202400031
- Thirabowonkitphithan P.,, R. Žalneravičius, A. Shafaat, D. Jakubauskas, J. Neilands, W. Laiwattanapaisal, T. Ruzgas. 2024. Electrogenicity of microbial biofilms of medically relevant microorganisms: potentiometric, amperometric and wireless detection. Biosensors & Bioelectronics 246: Article Number 115892.
- Žalneravičius R., A. Naujokaitis, V. Jasulaitienė, R. Rutkienė, R. Meškys, Dagys M. 2024. A 2D-to-3D morphology transitions of gold in organic acid electrolytes: Characterization and application in bioanode design. Applied Surface Science 642: 158654.
2023
- Andriukonis E., M. Butkevičius, P. Simonis, A. Ramanavičius. 2023. Development of a disposable polyacrylamide hydrogel-based semipermeable membrane for micro Ag/AgCl reference electrode. Sensors 23(5): 2510.
- Bagdžiūnas G.. 2023. Electrochemistry and spectroscopy-based biosensors. Biosensors-Basel 13(1): 9.
- Butkevičius M., J. Gaidukevič, V. Gurevičienė, J. Razumienė . 2023. Reduced graphene oxide/organic dye composites for bioelectroconversion of saccharides: application for detection of saccharides and α-amylase assessments. Biosensors-Basel 13 (12): Article Number 102
- Dudkaitė V., V. Kairys, G. Bagdžiūnas. 2023. Understanding the activity of glucose oxidase after exposure to organic solvents. Journal Of Materials Chemistry B 11(11), p. 2409-2416.
- Razumienė J., D. Leo, V. Gurevičienė, D. Ratautas, J. Gaidukevič, I. Šakinytė-Urbikienė. 2023. L-Glutamate biosensor for in vitro investigations: application in brain extracts. Chemosensors 11(8): 418.
- Sharrock A.V., J.S. Mumm, G. Bagdžiūnas, N. Čėnas, V. Arcus, D.F. Ackerley. 2023. The crystal structure of engineered nitroreductase NTR 2.0 and impact of F70A and F108Y substitutions on substrate specificity. International Journal of Molecular Sciences 24(7): 6633.
2022
- Dudkaitė V., G. Bagdžiūnas. 2022. Functionalization of glucose oxidase in organic solvent: towards direct electrical communication across enzyme-electrode interface. Biosensors-Basel 12(5): 335.
- Makaras T., J. Razumienė, V. Gurevičienė, G. Sauliutė, M. Stankevičiutė. 2022. Technical suitability and reliability of an in vivo and non-invasive biosensor-type glucose assessment as a potential biomarker for multiple stressors in fishes: an evaluation on Salmonids. Environmental Science and Pollution Research 29(27): 41187-41206.
- Miškinis J., E. Ramonas, V. Gurevičenė, J. Razumienė, M. Dagys, D. Ratautas. 2022. Capacitance-based biosensor for the measurement of total loss of l-amino acids in human serum during hemodialysis. ACS Sensors DOI 10.1021/acssensors.2c01342
- Neciporenko A., F. Ivanauskas, J. Dabulytė-Bagdonavičienė, A. Povilaitis, V. Laurinavičius. 2022. Nitrate removal in woodchip denitrification bioreactor - an approach combining mathematical modelling and pi control. Journal of Environmental Engineering and Landscape Management 30(1): 13-21
- Radveikienė I., D. Palinauskas, E. Ragauskaitė, G. Bagdžiūnas. 2022. Self-assembled cyclodextrins-based nanostructures on indium-tin-oxide for a detection of catecholamine neurotransmitters. Applied Surface Science 600: 154170
- Ramonas E., M. Butkevičius, S. Shleev, M. Dagys, D. Ratautas. 2022. Mechanistic characterization of an oxygen reduction reaction-driven, fully enzymatic and self-calibrating pH biosensor based on wired bilirubin oxidase. Sensors and Actuators B: Chemical 367: 132054
- Serapinas S., J. Gineitytė, M. Butkevičius, R. Danilevičius, M. Dagys, D. Ratautas. 2022. Biosensor prototype for rapid detection and quantification of DNase activity. Biosensors & Bioelectronics 213: 114475. IF 12.545
- Shafaat A., R. Žalneravičius, D. Ratautas, M. Dagys, R. Meškys, R. Rutkienė, J.F. Gonzalez-Martinez, J. Neilands, S. Bjorklund, J. Sotres, T. Ruzgas. 2022. Glucose-to-resistor transduction integrated into a radio-frequency antenna for chip-less and battery-less wireless sensing. ACS Sensors 7(4): 1222-1234.
- Tetianec L., I. Bratkovskaja, V. Časaitė, V. Gurevičienė, J. Razumienė, J. Stankevičiūtė, R. Meškys, M. Dagys, A. Laurynėnas. 2022. Efficient bi-enzymatic synthesis of aldonic acids. Green Chemistry 24(12): 4902-4908.
2021
- Baronas R., J. Kulys, L. Petkevičius. 2021. Modeling carbohydrates oxidation by oxygen catalyzed by bienzyme glucose dehydrogenase/laccase system immobilized into microreactor with carbon nanotubes. Journal of Mathematical Chemistry 59: 168-185.
- Bartusevičienė I., V. Vicka, A. Vickienė, L. Tetianec, M. Dagys, D. Ringaitienė, A. Klimašauskas, J. Šipylaitė. 2021. Conceptual model of adding antibiotics to dialysate fluid during renal replacement therapy. Scientific Reports 11(1): 23836.
- Budvytytė R., A. Milašiutė, D. Vitkus, K. Strupas, A. Gulla, I. Šakinytė, J. Razumienė. 2021. Tethered lipid membranes as a nanoscale arrangement towards non-invasive analysis of acute pancreatitis. Biomedicines 9(7): 755.
- Čeksterytė V., G. Treigytė, D. Matuzevičius, K. Jaškūnė, D. Navakauskas, B. Kurtinaitienė, R. Navakauskienė. 2021. Comparative proteomic profile in bee- and manually-collected Taraxacum officinale pollen. Journal of Apicultural Research doi 10.1080/00218839.2021.1969819
- Grybauskaitė-Kaminskienė G., V. Dudkaitė, G. Bagdžiūnas. 2021. Photophysical and semiconducting properties of isomeric triphenylimidazole derivatives with a benzophenone moiety. New Journal of Chemistry 45(42): 19746-19754.
- Javorskis T., A. Jurys, G. Bagdžiūnas, E. Orentas. 2021. Synthesis of C- and N-substituted 1,5,2,6-dithiadiazocanes -electrophilic-nucleophilic thioamination (ENTA) reagents. Advanced Synthesis & Catalysis 363(13): 3329-3335.
- Makaras T., M. Stankevičiūtė, E. Šidagytė-Copilas, T. Virbickas, J. Razumienė. 2021. Acclimation effect on fish behavioural characteristics: determination of appropriate acclimation period for different species. Journal of Fish Biology 99(2): 502-512.
- Radveikienė I., R. Vidžiūnaitė, R. Meškienė, R. Meškys, V. Časaitė. 2021. Characterization of a yellow laccase from Botrytis cinerea 241. Journal of Fungi 7(2): 143.
- Ramonas E., A. Shafaat, M. Dagys, T. Ruzgas, D. Ratautas. 2021. Revising catalytic "acceleration" of enzymes on citrate-capped gold nanoparticles. Journal of Catalysis 404: 570-578.
- Repečka D., V. Jauniškis, L. Karpus, E. Rembeza, I. Rokaitis, J. Zrimec, S. Povilonienė, A. Laurynėnas, S. Viknander, W. Abuajwa, O. Savolainen, R. Meškys, M. K. M. Engqvist, A. Zelezniak. 2021. Expanding functional protein sequence spaces using generative adversarial networks. Nature Machine Intelligence 3(4): 324-333.
- Šakinytė I., M. Butkevičius, V. Gurevičienė, J. Stankevičiūtė, R. Meškys, J. Razumienė.2021. Reagentless D-tagatose biosensors based on the oriented immobilization of fructose dehydrogenase onto coated gold nanoparticles- or reduced graphene oxide-modified surfaces: application in a prototype bioreactor. Biosensors-Basel 11(11): 466.
- Teišerskytė V., J. Urbonavičius, D. Ratautas. 2021. A direct electron transfer formaldehyde dehydrogenase biosensor for the determination of formaldehyde in river water. Talanta 234: 122657.
- Voitechovic E., J. Stankevičiūtė, A.Vektarienė, G. Vektaris, R. Jančienė, N. Kuisienė, J. Razumienė, R. Meškys. 2021. Bioamperometric systems with fructose dehydrogenase from Gluconobacter japonicus for D-tagatose. Electroanalysis 33(6): 1393-1397.
2020
- Bagdžiūnas G. 2020 Theoretical design of molecularly imprinted polymers based on polyaniline and polypyrrole for detection of tryptophan. Molecular Systems Design & Engineering 5: 1504-1512.
- Bagdžiūnas G.,, D. Palinauskas. 2020. Poly(9H-carbazole) as a organic semiconductor for enzymatic and non-enzymatic glucose sensors. Biosensors-Basel 10(8): AN 104.
- Bagdžiūnas G., D. Palinauskas, A. Ramanavičius. 2020. Towards colourless‐to‐green electrochromic smart glass based on a redox active polymeric semiconductor containing carbazole moiety. Dyes and Pigments 177: 108328.
- Čeksterytė V., B. Kurtinaitienė, K. Jaskūnė, J. Kretavičius. 2020. The influence of storage conditions on invertase, glucose oxidase activity and free acidity of bee bread and bee-collected pollen mixed with honey and vegetable oils. Journal of Apicultural Research 59: 862-875. IF 2.584
- Gružauskaitė J., J. Jasinskaitė, R. Meškys, G. Gaidamavičienė, A. Žalga, A. Laurynėnas, L. Tetianec, M. Dagys. 2020. Gold-coated magnetic nanocatalyst containing wired oxidoreductases for mediatorless catalysis of carbohydrate oxidation by oxygen. Catalysis Communications 135: AN 105848
- Makaras T., J. Razumienė, V. Gurevičienė, I. Šakinytė, M. Stankevičiūtė, N. Kazlauskienė. 2020. A new approach of stress evaluation in fish using β-d-Glucose measurement in fish holding-water. Ecological Indicators 109: 105829.
- Meškytė E., S. Keskas, Y. Ciribilli. 2020. MYC as a multifaceted regulator of tumor microenvironment leading to metastasis. International Journal of Molecular Sciences 21:3234.
- Radveikienė I., I. Pilotaitė, R. Dainytė, R. Vidžiūnaitė. 2020. Biosynthesis, purification, characterization and immobilization of laccase from Lithothelium sp. Chemija 31: 178-190.
- Ramašauskas L., R. Meškys, D. Ratautas. 2020. Real-time glucose monitoring system containing enzymatic sensor and enzymatic reference electrodes. Biosensors and Bioelectronics 164: 112338.
- Ratautas D., M. Dagys. 2020. Nanocatalysts containing direct electron transfer-capable oxidoreductases: recent advances and applications. Catalysts 10: 9.
- Razumienė J., V. Gurevičienė, I. Šakinytė, L. Rimsevičius, V. Laurinavičius. 2020. The synergy of thermally reduced graphene oxide in amperometric urea biosensor: application for medical technologies. Sensors 20: AN 4496.
- E. Ros, M. Reig, C.Voz, G. Bagdžiūnas, P. Ortega, D. Velasco, J. Puigdollers. 2020. Shedding light on the negative differential resistance effect observed in organic thin-film transistors. ACS Applied Electronic Materials 2: 1574-1582.
- Stanislauskienė R., A. Laurynėnas, R. Rutkienė, A. Aučynaitė, D. Tauraitė, R. Meškienė, N. Urbelienė, A. Kaupinis, M. Valius, L. Kalinienė, R. Meškys. 2020. YqfB protein from Escherichia coli: an atypical amidohydrolase active towards N4-acylcytosine derivatives. Scientific Reports 10:788. IF 4.379
- Urbelienė N., R. Meškienė, M. Tiškus, R. Stanislauskienė, A. Aučynaitė, A. Laurynėnas, R. Meškys. 2020. A rapid method for the selection of amidohydrolases from metagenomic libraries by applying synthetic nucleosides and a uridine auxotrophic host. Catalysts 10: 445.
- Voitechovič E., A. Vektarienė, G. Vektaris, R. Jančienė, J. Razumienė, V. Gurevičienė.2020. 1,4-Benzoquinone derivatives for enhanced bioelectrocatalysis by fructose dehydrogenase from gluconobacter japonicus: towards promising D-fructose biosensor development. Electroanalysis 32: 1005-1016
2019
- Baronas R., J. Kulys, L. Petkevičius. 2019. Computational modeling of batch stirred tank reactor based on spherical catalyst particles. Journal of Mathematical Chemistry 57: 327-342
- Čeksterytė V., Borutinskaitė V., D. Matuzevičius, G. Treigytė, D. Navakauskas, B. Kurtinaitienė, R. Navakauskienė. 2019. Evaluation of proteome profiles of Salix spp. pollen and relationship between glucose oxidase activity and pollen content in willow honey. Baltic Forestry 25: 83-96.
- Gineitytė J., R. Meškys, M. Dagys, D. Ratautas. 2019. Highly efficient direct electron transfer bioanode containing glucose dehydrogenase operating in human blood. Journal of Power Sources 441: 227163
- Laurinavičius V., F. Ivanauskas, A. Neciporenko. 2019. Drug delivery mathematical modeling for pressure controlled bioreactor. Journal of Mathematical Chemistry. 57: 1973-1982.
- Laurynėnas A., M. Butkevičius, M. Dagys, S. Shleev, J. Kulys. 2019. Consecutive Marcus electron and proton transfer in heme peroxidase compound II-catalysed oxidation revealed by Arrhenius plot. Scientific Reports 9: AN 14092.
- Ledas Ž., R. Šimkus, R. Baronas. 2019. Computational modeling of self-organization of bacterial population consisting of subpopulations of active and passive cells. Journal of Biological Sciences 27: 365-381.
- Ramonas E., D. Ratautas, M. Dagys, R. Meškys, J. Kulys. 2019. Highly sensitive amperometric biosensor based on alcohol dehydrogenase for determination of glycerol in human urine. Talanta 200: 333-339.
- Rekovič L., L. Kosychova, I. Bratkovskaja, R. Vidžiūnaitė. 2019. Synthesis and spectral characterization of novel 1,5-benzodiazepine oxime derivatives. Journal of the Serbian Chemical Society 84: 343-353.
- Vaitkutė G., I. Bratkovskaja, V. Časaitė, J. Stankevičiūtė, R. Meškys, L. Tetianec. 2019. Electron transfer mediators for PQQ dependent soluble glucose dehydrogenase catalyzed lactose oxidation reaction. Chemija 30: 194-200.
- Valldeperas M., A. Salis, J. Barauskas, F. Tiberg, T. Arnebrandt, V. Razumas, M. Monduzzi, T. Nylander. 2019. Enzyme encapsulation in anostructured self-assembled structures: Toward biofunctional supramolecular assemblies. Current Opinion in Colloid&Interface Science 44: 130-142.
- Voitechovič E., R. Jančienė, G. Mikulskienė, A. Vektarienė, V. Vektaris, J. Razumienė. 2019. Synthesis and DFT characterisation of 2-arylamino-1,4-benzoquinone derivatives as potential electron transfer mediators. Chemija 30: 115-126.
2018
- Ratautas, D., Ramonas, E., Marcinkevičienė, L., Meškys, R, Kulys, J. 2018. Wiring Gold Nanoparticles and Redox Enzymes: A Self‐Sufficient Nanocatalyst for the Direct Oxidation of Carbohydrates with Molecular Oxygen. hemCatChem 10(5), pp.971-974.
- Gruskiene, R., Krivorotova, T., Staneviciene, R., Ratautas, D., Serviene, E. and Sereikaite, J., 2018. Preparation and characterization of iron oxide magnetic nanoparticles functionalized by nisin. Colloids and Surfaces B: Biointerfaces 169, pp.126-134.
- Baronas, R., Kulys, J. Petkevicius, L., 2018. Modelling the enzyme catalysed substrate conversion in a microbioreactor acting in continuous flow mode. Nonlinear Analysis-Modelling and Controll 23(3), pp.437-456.
2017
- Dagys M., Laurynėnas A., Ratautas D., Kulys J., Vidžiūnaitė R., Talaikis M., Niaura G., Marcinkevičienė L., Meškys R., Shleev S. 2017. Oxygen electroreduction catalysed by laccase wired to gold nanoparticles via the trinuclear copper cluster. Energy Environmental Science 10: 498-502.
- Tetianec L., Chaleckaja A., Kulys J., Janciene R., Marcinkeviciene L., Meskiene R., Stankeviciute J., Meskys R. 2017. Characterization of methylated azopyridine as a potential electron transfer mediator for electroenzymatic systems. Process Biochemistry 54: 41-48.
- Ratautas D.,Tetianec L., Marcinkevičienė L., Meškys R., Kulys J. 2017. Characterization of methylated azopyridine as a potential electron transfer mediator for electroenzymatic systems. Biosensors Bioelectronics 98: 215-221
- Gaidukevic J., Razumiene J., Sakinyte I., Rebelo S. L.H., Barkauskas J. 2017. Study on the structure and electrocatalytic activity of graphene-based nanocomposite materials containing (SCN)n. Carbon 118: 156 – 167.
2016
- Ratautas D., Laurynėnas A., Dagys M., Marcinkevičienė L., Meškys R., Kulys J. 2016. High current, low redox potential mediatorless bioanode based on gold nanoparticles and glucose dehydrogenase from Ewingella Americana. Electrochimica Acta 199: 254-260.
- Ivanauskas F., Katauskis P., Laurinavicius V. 2016. Impact of convective transport and inert membrane on action of bio-catalytic filtre Journal of Mathematical Chemistry. 54(6): 1221-1232.
- Šimkus R., Meškienė R., Ledas Ž., Baronas R., Meškys R. 2016. Microtiter plate tests for segregation of bioluminescent bacteria. Luminescence 31(1): 127-134.
2015
- Razumiene J., Sakinyte I., Barkauskas J., Baronas R. 2015. Nano-structured carbon materials for improved biosensing applications. Applied Surface Science 334: 185-191.
- Razumiene J., Cirbaite E., Razumas V., Laurinavicius V. 2015. New mediators for biosensors based on PQQ-dependent alcohol dehydrogenases. Sensors and Actuators B: Chemical 207: 1019-1025.
- Ratautas D., Marcinkevičienė L., Meškys R., Kulys J. 2015. Mediatorless electron transfer in glucose dehydrogenase/laccase system adsorbed on carbon nanotubes. Electrochimica Acta 74: 940-944.
- Tetianec L., Chaleckaja A., Vidžiūnaitė R., Kulys J., Bachmatova I., Marcinkevičienė L., Meškys R. Development of a laccase/syringaldazine system for NAD(P)H oxidation. Journal of Molecular Catalysis. B: Enzymatic. Amsterdam: Elsevier. 2014, Vol. 101, p. 28-34.
- Dagys M., Lamberg P., Shleev S., Niaura G., Kulys J., Arnebrant Th., Ruzgas T., Comparison of bioelectrocatalysis at Trichaptum abietinum and Trametes hirsuta laccase modified electrodes. Electrochimica Acta. Oxford : Pergamon-Elsevier Ltd. 2014, Vol. 130, p. 141-147.
- Ivanauskas F., Katauskis P., Laurinavičius V. Mathematical modeling of biosensor action in the region between diffusion and kinetic modes. Journal of Mathematical Chemistry. 2014, Vol. 52, p. 689-702.
- Simelevicius D., Petrauskas K., Baronas R., Razumiene J. Computational Modelling of Mediator Oxidation by Oxygen in Amperometric Glucose Biosensor. Sensors. 2014, Vol. 14, No. 2, p. 2578-2594.
- Snopok B., Naumenko D., Servienė E., Bružaitė I., Stogrin, Kulys J., Snitka V., Evanescent-field-induced Raman scattering for bio-friendly fingerprinting at sub-cellular dimension. Talanta. Amsterdam: Elsevier Science. 2014, vol. 128, p. 414-421.
- Barkauskas J., Dakševič J., Budrienė S., Razumienė J., Šakinytė I. Adhesion of graphene oxide on a transparent PET substrate: a study focused on the optimization process. Journal of Adhesion Science and Technology. 2014, Vol. 28, No. 20, p. 2016-2031.
- Laurinavicius V., Razumiene J., Gureviciene V. Bio-electrochemical Conversion of Urea on Carbon Black Electrode and Application. IEEE Sensors. 2013, Vol. 13, No. 6, p. 2208-2213.
- Ašeris V., Baronas R., Kulys J. Modelling the biosensor utilising parallel substrates conversion. Journal of Electroanalytical Chemistry. 2012, Vol. 685, p. 63–71.
- Kulys J., Bratkovskaja I., Ašeris V., Baronas R. Electrochemical Peroxidase-Catalase Clark-Type Biosensor: Computed and Experimental Response. Electroanalysis. 2013, Vol. 25, No. 6, 1491 – 1496.
Projects
National projects
Reseach Council of Lithuania
Researcher groups projects
- "Development of the electrochemical biosensor for the detection of single-nucleotide polymorphisms (FindSNPs)", project leader dr. Dalius Ratautas, 2023-2025.
Technology development programm
- "Development of a bioelectrochemical L-amino acid-urea analyzer for monitoring of intensive care patients (AminoUreaSense) ", project leaderdr. Dalius Ratautas, partner UAB "Bioanalizės sistemos", 2023-2024.
Postdoctoral fellowships
- "Ultrasensitive monitoring of medically relevant biomarkers on nanostructured surfaces (NanoBioSens)", dr. Rokas Žalnėravičius, 2022-2024.
List of past international and national projects
International projects
European Joint Programme on Rare Diseases
- Unveiling the role of glutamate in dopamine transporter deficiency syndrome (URGENT), leader dr. J. Razumienė, coordinator Universite de Mons, Belgium. 2020-2023.
7th Framework Programme
- Chemical Bioanalysis (CHEBANA) , partners - Institute of Biochemistry, vadovas prof. Juozas Kulys, coordinator - Universitaet Regensburg, Germany, 2010 – 2014. Programm "People", "Marie-Curie Action: "Initial Training Networks" (ITN)
-
7 FW Leonardo da Vici Program. „Food Industry - Food Legislation, Impact Analysis, Training and Cooperation Network in Europe -E-Learning“ (2012-2014). Prof. V. Laurinavicius.
The EUREKA Network Application
- E! 8835. Multiple biosensor device for hemodialysis patients Dr. J. Razumiene, 2014-2016.
European cooperation in Science and Technology (COST)
- CM0701 "Cascade Chemoenzymatic Processes – New Synergies Between Chemistry and Biochemistry", dr. J. Razumienė, coordinator Istituto di Chimica del Riconoscimento Molecolare, Italija, 2008-2012
National grants
Central Project Management Agency.
- Development of Biosensor Research and Engineering Competence and Technology Transfer Centre (BIOSENSE) (No. 01.2.2-CPVA-K-703-03-0010). dr. M. Dagys. 2020–2023.
Lithuanian Science Programmes and Projects supported by Research Council of Lithuania
Targeted Research in Smart Specialization Areas
- Biosensor Platform for Fast, Cheap and Accurate Quantification of Amino Acids in Patients Undergoing Renal Replacement Therapy (DIALSENS) (No. 01.2.2-LMT-K-718-01-0019). Dr. D. Ratautas. Partner – Vilnius University Hospital Santaros Klinikos. 2020–2024.
- Development of Non-invasive method platform for early diagnostics and prognosis of acute pancreatitis (No. 01.2.2-LMT-K-718-01-0025). Dr. Julija Razumienė. Partner – Vilnius University Hospital Santaros Klinikos. 2018 – 2022
- Biocatalytic systems for conversion of non-starch poli- and oligosaccharides (No. 01.2.2-LMT-K-718-01-0019). Dr. Marius Dagys. 2018 – 2022.
Research groups projects
- Supramolecular recognition-based sensors for electro- detection of biomolecules. Dr. Gintautas Bagdžiūnas, 2020-2022.
- Self-organization of E. coli and their mutants near three phase contact line. Dr. R. Šimkus, 2014-2016.
- Bee products enriched with plant components, the composition and properties.Dr. B. Kurtinaitiene, 2012-2015
- Biotechnology and Biopharmacy: fundamental and applied research, activity 1.1.4. (2012-2015) Head of the Action Dr. J. Razumiene.
- Non- invasive approach to early diagnosis and prognosis of acute severe pancreatitis (AP). (2017-2021) Dr. J. Razumiene.
Contractual Research
Foundation of dr. Bronislovas Lubys. Applied Charity and Support.“Amperometric fast response method for measurement of urea concentration in industrial media”.(2015 – 2016) dr. Marius Dagys.
Personnel
Head of department
Dr. Marius Dagys
852234387
Research staff
Dr. Julija Razumienė chief researcher 852234388 |
Dr. Gintautas Bagdžiūnas senior researcher 85224393 |
Dr. Dalius Ratautas senior researcher 852234389 |
Dr. Audrius Laurynėnas researcher 852234387 |
Dr. Ieva Šakinytė researcher 852234388 |
Dr. Lidija Tetianec researcher 852234391 |
dr. Eimantas Ramonas researcher |
Dr. Rokas Žalnėravičius postdoc researcher |
Marius Butkevičius junior research fellow 852234387 |
Irina Bratkovskaja junior researcher 852234391 |
Prof. habil. dr. Juozas Kulys emeritus |
Prof. habil. dr. Valdas Laurinavičius emeritus 852234389 |
Vida Gurevičienė biochemist 852234388 |
PhD students
Martynas Katelynas | Kamilė Ratkevičiūtė | Skomantas Serapinas |
Technical staff
Algimantas Jonuška engineer |
Nijolė Baliuckienė technician 852234400 < |
Jadvyga Matulevič Ilinykh technician |
Laima Ginotienė technician 852234400 |