Neurotransmitters (NTs) are essential for overseeing behavioural and physiological processes within the nervous system. Discrepancies in NT levels have a direct correlation with a range of neurological ailments and various psychiatric conditions as well as neurodegenerative disorders. Consequently, promptly and continuously monitoring NT levels is paramount for a thorough understanding of neurological operations and early detection of disorders. Furthermore, real-time monitoring of various neurochemicals with high spatial resolution in multiple brain regions in vivo can elucidate neural circuits related to the brain-computer interface. We are looking and engineering for enzymes that can be used to selectively detect individual neurotransmitters such as dopamine, adrenalin, noradrenalin, serotonin, D-amino acids, L-glutamate, and γ-aminobutyric acid (GABA).
Figure. Monolayer of the enzyme as a recognition element for the detection of analytes onto the electrode
We are currently in the process of developing biosensors for a range of analytes, including:
- Carbohydrates: glucose, galactose, lactose, etc.
- General healthcare analytes: cholesterol, lactate, pyruvate, xanthine, oxalate, uric acid, urea, free fatty acids, glycerol, hydrogen peroxide, etc.