On April 30, we invite you to two seminars by guest speakers from National Taiwan University, who will present the latest research on the role of RNA helicases in splicing regulation and the application of CRISPR/Cas9 technologies in cancer studies.

Date: April 30 (Tuesday)
Place: Room R401, Life Sciences Center

10:00 AM
Dr. Kao Ching-Yang
Manager, Gene Therapy Core, Center for Frontier Medicine, National Taiwan University Hospital
Presentation topic: From Recognition to Resolution: Dynamic Control of Splice Site Selection by RNA Helicases

Dr. Kao will present the mechanisms by which RNA helicases regulate the dynamics of alternative splicing – from the initial recognition of signals to the final selection of splice sites. The presentation will also cover how disruptions in these processes are linked to disease.

10:50 AM
Dr. You-Tzung Bob Chen
Associate Professor, Graduate Institute of Medical Genomics and Proteomics, National Taiwan University College of Medicine
Presentation topic: Multiplex CRISPR/Cas9-mediated Somatic Mutagenesis for Cancer Studies

The presentation will introduce the ICE CRIM mouse model developed for somatic mutagenesis in cancer research. Using this model, the effects of mismatch repair deficiency on tumor development and the cross-species conservation of the microsatellite instability phenotype were investigated.

You will find the speakers’ bios and abstracts attached to this email.