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Course unit title

Scientific direction

Scientific code

Faculty

Department (s)

Eukaryotic microorgnism physiology

Biology N010

Life Sciences Centre

Institute of Biosciences

Total number of credits

10

Mode of studies

Number of credits

Mode of studies

Number of credits

Lectures

0

Consultations

3

Self-studies

7

Seminars

0

Aims of course

Course is focused on the knowledge of the fungal and yeast physiology processes at the molecular, cellular and ecosystems level of organizations. Doctoral-level studies in microbiology focus on advanced application of scientific techniques to study eukaryotic microorganisms and how they affect human life, technology, the ecosystem, and other factors in natural science, accent on the next generation of advanced technology used in development of biology-based technologies that provide significant advantages at a commercial level as well.

Main topics

The chemistry of the mycelium. Specific fungal metabolites. Primary metabolism and special aspects (aerobe and anaerobe respiration, cyanide resistant respiration, primary biosynthesis). C, N and P metabolism in fungi. The polysaccharides of fungi. The biosynthesis of trehalose, plant and fungal trehalases, terpenoid diversity in fungi. Secondary metabolism. The specific secondary metabolites of fungi. Synthesis of mycotoxins, pigments, antibiotics and other medicinal substances. Allelopathy. Regulation of metabolism and division. Internal and external regulatory factors. Signals and signal transduction pathways. Cell growth and the synthesis of the cell wall. Structure, growth and differentiation of the mycelium. Trophic growth, nutrient uptake, transport, translocation. The kilotroph nutrition. Digestion processes of fungi. Induction and classification of extramycelial enzymes. Effect of the environment factors on growth and differentiation. Termophilic and psichrophilic fungi. Physiology of the sexual and asexual reproduction. Genetic and hormonal regulation of the vegetative – reproductive transition. Sexpheromons in fungi. Mating and meiosis. Induction of primordium and fruit body formation. Process of spore formation. Induction and environmental conditions of spore germination. The most important biodegradation processes of fungi. Enzymes of the lignocellulase complex, induction, and regulation of the cellulose decomposition. The brown rot fungi. Lignin decomposition, enzymes (lignin peroxidase, laccase, tyrosinases, phenoloxidase), relationships between structure and function. Enzymes of the white rot fungi. Delignification with industrial and biological methods. Stress physiology of fungi and the role of phytopathogenic fungi in plant diseases. Parasitism and biocontrol. Physiological bases of culturing fungi. Two-step fermentation, solid and liquid phase cultures, composting.

Main literature

  • D.H.Jennings. The Physiology of Fungal Nutrition 1st Edition.  2007. Cambridge University Press.
  • D.H. Griffin. Fungal physiology. 1996. Wiley-Liss Inc., Publ., NY. USA
  • K. S. Bilgrami. Physiology of Fungi. 2011. Scientific Publishers. 
  • J. R. Dickinson, M.Schweizer. Metabolism and Molecular Physiology of Saccharomyces cerevisiae, 2nd Ed. 2004. CRC Press.
  • Journals: Journal of Fungi; Fungal Biology; Yeast; Journal of Yeast and Fungi Research; FEMS Yeast Research; Mycology.

Assessment strategy

Assessment criteria

Seminar presentation

The oral examination – seminar- presenting the novel research results  focus on to the areas of microbiology chosen by the student and exam committee. Duration of presentation 30 - 45 min.

Coordinator(s)

Name, Surname

Pedagogical

rank

Scientic

degree

Email

Eglė Lastauskienė prof. dr.

Approved by the Council of Doctoral School of Life Sciences Center No (4.10)600000-KT-… on the 14th of October 2021

Chairman dr. Daiva Baltriukienė

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