Organic chemistry, materials chemistry, biochemistry, biomedicine, chemical synthesis, rational design of materials with desirable properties, pharmacology, medicinal drugs, studies of biological activity, synthetic and natural compounds, investigation of properties of new materials, spectroscopy, high energy materials, analytical methods, spectroscopy, crystallography, X-Ray analysis, thermal analysis, mass-spectrometry, aromatic and heterocyclic derivatives, nitrocompounds, N-oxides, quinones, polyphenols, bioactive substances, bioremediation, toxicology, ecotoxicology.
Present Position:
Senior Researcher, Vilnius University, Life Science Center, Institute of Biochemistry
Education:
1981 - Chemist, Vilnius University, Faculty of Chemistry (1976-1981); 1999 - PhD in Chemistry, Vilnius University, Institute of Chemistry, Institute of Biochemistry
Experience (Past Positions):
Scientific research, project management, project expertise (FP6, FP7 and HORIZON 2020 projects expert (2006-...), information analysis, consultant for PhD student, head and consultant for master degree thesis preparation (3 students). Reviewer of manuscripts of the journals: Chemistry of Heterocyclic compounds, Journal of Energetic Materials, Central European Journal of Energetic Materials, European Journal of Medicinal Chemistry, Bioorganic and Medicinal Chemistry, IJMS and some ACS journals.
Design of antiparasitic drugs (Summer practice courses)
National Cancer Institute (NCI), USA, Maryland, Bethesda Paster Institute, Montevideo, Uruguay Universite Paris Sud, Pharmacy, Department, France Pardubice University, Institute of Energetic Materials, Czech Rep. Latvian Institute of Organic Synthesis, Riga, Latvia
Projects and Grants:
1995–1997 EC PECO No. CIPD CT 940045 European network on studies of flavoenzymes. Researcher. 1996–2000 Lithuanian State Science and Studies Foundation project “Laser photosensitization in tumour therapy”. Researcher. 1997–1999 NATO Collaborative Linkage Grant No. HTECH.LG972012 Enzymatic and pulse-radiolysis studies of nitroheterocyclic compounds. Researcher. 2001–2004 Lithuanian Science Foundation project “Light in biomedicine”. Researcher. 2003 Lithuanian Science Foundation project "Influence of mieloperoxidase to poliphenol cytotoxicity". Coordinator. 2005 Lithuanian Science Foundation project "Novel high energy nitroaromatic compounds: investigation of their oxidation properties" T-05153, Nr. T-25/05. Coordinator. 2005–2007 COST B22 “Drug development for parasitic diseases”. National representative, MC member. 2007–2011 COST CM0603 “Free Radicals in Chemical Biology”. Researcher. 2009–2012 COST CM0801 “New Drugs for Neglected Diseases", Coordinator. 2014–2018 COST CM1307 “Targeted chemotherapy towards diseases caused by endoparasites”. National representative (Coordinator). 2008–2010 European network Leonardo da Vinci project: "Increasing competencies in European Explosives Sector" (EUExcert project). National Coordinator. 2007–2008 Lithuanian Science Foundation high technology project "A distant detection of chemical warfare pollution and explosive products" No.200P-51/07/2007-BI. Researcher. 2011–2012 Research Council of Lithuania, project MIP-080/2011 "Heterocyclic N-Oxides: Synthesis, Cytotoxicity, and Interaction with Target Enzymes". Coordinator. 2011–2015 Research Council of Lithuania supported Global dotation project VP1-3.1-ŠMM-07-07-K-01-103 “Molecular mechanisms of toxicity and anticancer activity: enzymatic redox reactions, cytotoxicity, signal transduction and proteomics”. Researcher. 2014–2015 Lithuania-Ukraine Programme: Investigation of L- and D-lactate: cytochrome с oxidoreductases isolated from the recombinant yeast Hansenula polymorpha and their usage for construction of amperometric biosensors. Researcher. 2013–2014 Lithuania-Belarus Programme: The characterization of the interprotein interaction and the modulators of the redox equivalent transfer in steroid hydroxylation systems. Researcher. 2014–2016 Lithuanian Research Council project MIP-032/2014 „New generation N-heterocyclic quinones: rational synthesis and elucidation of anticancer activity“. Researcher. 2011–2015 Molecular Mechanisms of Toxicity and Antitumor Activity of Quinones and Polyphenols: Enzymatic Redox Cytotoxicity, Signal Transduction, and Proteomics. European Social Fund under the Global Grant measure VP1-3.1-ŠMM-07-K-01-103 Research Council of Lithuania. Researcher. 2018–2021 Redox chemistry, biochemistry and cytotoxicity of aromatic nitrocompounds and N-oxides: new insights (No. DOTSUT-34/09.33-LMT-K712-01-0058). Researcher. 2019–2020 Lithuanian–French Programme "Gilibert": "Caractérisation du flavointeractome de l'agent antipaludique plasmodione et de ses métabolites". Researcher.
Other Related Activities:
Member of Lithuanian Biochemical Society, member of Lithuanian Mycological Society, Nominated foreign member of Sweden Detonation Society, COST Expert, MC member.
