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Gintaras Valincius  

Phone: +370 675 33278
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Research Group

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Research Interests: Bioelectrochemistry, electrochemical impedance spectroscopy, artificial phospholipid bilayers, interaction with membrane proteins, structure and imaging of membrane proteins by AFM, and high resolution fluorescence microscopy techniques, neutron techniques for membrane protein studies. 
Present Position: Research professor, Life Sciences Center, Vilnius University
Head of the Division of Bioelectrochemistry and Biospectroscopy
Education:
PhD in Natural Sciences 
Experience (Past Positions): 1980–1984 - research assistant, Vilnius University, Department of Physical Chemistry   
1984–1988 - assistant professor, Vilnius University, Department of Physical Chemistry   
1988–1998 - associate professor, Vilnius University, Department of Physical Chemistry   
1998–2002 - Visiting researcher, National Institute of Standards and Technology, Department of Biotechnology, Gaithersburg, Maryland, USA
2002–2011 -  associate professor, Vilnius Gediminas Technical University, Department of Chemistry and Bioengineering
2011–2017 - professor, Vilnius Gediminas Technical University, Department of Chemistry and Bioengineering
2002–2010 - Senior researcher, Institute of Biochemistry, Department of Bioelectrochemistry and Biospectroscopy, Vilnius University 
2010–present - Resear professor, professor, head of the Department of Bioelectrochemistry and Biospectroscopy
2017–2022 - Director, Life Science Center, Vilnius University
2022–present - Executive Director, Life Sciences Center, Partnership Institute for Genome Editing Technologies 
Physical Chemistry: Chemical Thermodynamics and Chemical Kinetics 
Supervision of Doctoral Students: During the last 10 years, the following PhD projects were commited under the supervision of Gintaras Valinčius:
   Completed projects: Ilja Ignatjev, Tadas Ragaliauskas, Mindaugas Mickevičius, Tadas Penkauskas, Indrė Aleknavičienė,
   Ongoing projects: Shiva Bilan, Filipas Ambrulevičius
Serving as a consultant: Martynas Talaikis (defended in 2021), VU ChGF, Inga Gabriūnaitė (defended in 2021) and Tomas Sabirovas (defended in 2020), VU ChGF
Awards: Lithuanian Science Prize
The Knight's Cross of the Order of the Grand Duke Gediminas of Lithuania 
Publications: LABT_LMAVB
Academic Cooperation: Dr. D. J. Vanderah, NIST/UMD IBBR, Rockville, MD, USA
Dr. F. Heinrich, NIST Center for Neutron Research, Gaithersburg, MD, USA
Dr. J. Andersson, Vienna Technical University, Austria
Dr. Mathias Loesche, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA 

Projects and Grants:

2012 - "Immobilized Phospholipid Membranes for Protein Membrane Interaction Studies (Imfabite)" Contract No. MIP-096/2011, project leader.
2013 - "Molecular Mechanisms of Alzheimer‘s Disease (Malpalma)" Contract No. LIG-004/2011, principal investigator at partner Institution (project leader).
- Separation and Characterization of Toxic Amyloid Species Implicated in Alzheimer's Disease. Bilateral Collaboration in Research and Development Program “Gilibert” Contract No. TAP-15/2011, principal investigator.
2005 - Detection of interactions of phospholipid membranes and bacterial toxins by elevtrochemical impedance spectroscopy LVMSF Nr. T31/07, project leader.
2013–2015 - “Miniaturized Phospholipid Biosensors (MiniFob)”, European Social Fund project. Contract No. VP1-3.1-ŠMM-0-V-02-024, project leader.
2019–2022 - Quantitative assessment of the phospholipid membrane damage exerted by the pore-forming toxins QAPHOMEDA. Nr. S-MIP-19-33. Research Council of Lithuana. Project leader.
- Biosensors for the detection of toxins BIOSENTOX Joint project with industrial partner UAB Energenas, funded by Lithuanian Business Support Agency, porject leader.
2013 - Spectroscopic and electrochemical investigation of biological and model self-assembled systems No. RD/2013/28 UAB ALTECHNA R&D. Principal investigator.
2012 - Investigation and testing of SERS active substrates Contract No. RD/2012/80 UAB ALTECHNA R&D. Principal investigator.

Improvement of Qualification, Certificates: Vilnius University senior management qualification upgrade courses 
Research Dissemination:

1) G. Valincius, R. Budvytyte, D.J. Vanderah. Interaction of β-amyloid with phospholipid membranes: implications for bioanalysis. International Translational Neuroscience Conference. Kaunas. June 16–17, 2011 (invited talk).
2) G. Valincius, T. Meskauskas, M. Mickevicius. Electrochemical Impedance of Tethered Bilayer Membranes. ICNT, International Conference on Nanoscience +Technology, Paris, France. July 23–27, 2012. (oral presentation),
3) G. Valinčius, R. Budvytytė, M. Jankunec, T. Penkauskas. Reconstitution of cholesterol dependent cytolysins into tethered bilayer membranes. Pore-Forming Toxins: a meeting in memory of Gianfranco Menestrina, 28–30 August 2014, Trento, Italy. (oral presentation).
4) G. Valinčius, R. Budvytyte, T. Penkauskas, M. Pleckaityte, and A. Zvirbliene Phospholipid Sensors for Detection of Bacterial Pore-Forming Toxins. 2014 ECS and SMEQ Joint International Meeting, Cancun, Mexico, October 5–10, 2014. (oral presentation).
5) G. Valinčius, M. Mickevičius, T. Penkauskas. Characterization of Tethered Bilayer membranes by the Electrochemical Impedance Spectroscopy. PacSurf (Pacific Rim Symposium on Surfaces, Coatings and Interfaces), Kohala Coast, Hawaii, December 7–11, 2014, (oral presentation).
6) G. Valinčius. Activity of pore-forming cholesterol dependent cytolysins assessed by dielectric damage of tethered bilayer membranes. May 11–14, 2015, Prato, Italy (oral presentation).
7) G. Valinčius. Electrochemical Impedance of Tethered Bilayer Membranes. International ISI sponsored conference "Chemistry and Chemical Technology 2016". April 28–29, 2016, Vilnius (invited talk).
8) G. Valincius. Fabrication of phospholipid biosensors for bacterial toxins. June 14–17, 2016. Helsinki (oral presentation).
9) G. Valincius, G. Dreizas, T. Penkauskas, T. Meskauskas. Electrochemical Impedance Spectroscopy of Tethered Bilayers: Effect of Random Distribution of Defects in Membrane. International Society of Electrochemistry Meeting. Providence. RI, USA. Aug.29–Sept.02, 2017 (invited talk).
10) G. Valincius et al. Electrochemical Impedance Spectroscopy: Tool for Structure and Function Studies of Bilayers Populated with Ion-Conducting Pores. Biannual meeting of Bioelectrochemical Society. April 2–9, 2022 , Antwerp. (Keynote lecture).

Other Related Activities: 2022–present - Member of Secretrary General NATO Advisory Expert Group on Transformative and Discruptive Technologies 
2019–2021 - Advisor to the Minister of Science and Education of Lithuania
2018 - Group Leader for Evaluation of Implementation of Smart Specialisation Strategy of Lithuania 
Languages: Lithuanian (native), English, French, Russian

 

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