Institute of Biochemistry is a research centre focusing on investigation of biochemical and genetic principles of cell functioning - genetic engineering, biocatalysis, signaling and cell regulation, basic and applied aspects of enzyme chemistry, biosensor design, synthesis of the organic compounds.
The staff of the Institute consists of experienced, qualified and competent more than 60 scientists, 35 doctoral students with expertise in the field of biochemistry, microbiology, cellular biology and chemistry.
The Institute of Biochemistry operates at the interface between medicine, biology and chemistry to investigate the structure and function of cells, biomolecules, (bio)materials.
Institute provides infrastructure for postgraduate studies leading to Masters and PhD qualifications.
Main R&D activities
Investigation and application of biocatalysts and self-assembling structures
- Screening, development and application of biocatalysts
- Metabolic pathways in microorganisms
- Genetic diversity and molecular biology of bacteria and bacteriophages
- Metabolism of modified nucleotides and nucleosides
- Self-assembling lipid systems and their interactions with proteins
- Investigation of the electron transport in proteins, the structure and functioning of enzymes
- Development and investigation of bioelectrocatalytical systems for biosensors and bioreactors
- Synthesis, biochemical characterization and cytotoxicity studies of redox active xenobiotics and other organic compounds
- Search and development for methods of synthesis of bioorganic compounds as modulators of biologic processes
Signaling pathways and epigenetic regulation of tumor and stem cells
- Studies of the molecular mechanisms of signal transduction in normal and cancer cells
- Epigenetic regulation in cancer and stem cells
- High-throughput proteomics analysis of cell signaling
- Elucidation of artificial microstructures and nano-particles on cell functioning
- Adult stem cells properties and their sensitivity in vitro and in vivo
- Cell technologies for the regenerative medicine: development and evaluation using biological models
Research services
Screening of novel enzymes for biocatalysis
- Biodiversity of catabolic pathways.
- Screening and development of enzymes including metagenomic libraries and genetic engineering.
- Application of enzymes for bioconversion and biosensors.
- Understanding of the genetics, biochemistry and mechanisms of biodegradation of various N-heterocycles (hydroxy-, methyl- and carboxypyridines and pyrazines) and development of biocatalytic processes for conversion of glycerol, starch and other carbohydrates.
Protein analysis and their sub-subcellular localization
- Protein identification, purity and stability analysis.
- Peptide de novo sequencing.
- Protein-protein complex formation (dimerization, oligomerization, etc.) analysis.
- Identification of protein chemical modification (cell signaling).
- Proteome differential screening (marker discovery).
- Hypothesis-driven protein analysis (marker verification).
- Protein co-localization in cells (study of protein function).
Cell technologies
- Microinjection of proteins and other substances into the live cell to study their function.
- Screening of novel chemical compounds for potential therapeutic activity.
- Studies of cytotoxicity.
- Cellular microenvironment modeling in vitro.
- Construction and testing of scaffolds designed for regenerative medicine.
- Fabrication of artificial tissues.
In vivo testing
- Preclinical studies of novel materials and chemical compounds: acute and repeated dose toxicity tests (oral, dermal, skin irritation, eye irritation, skin sensitization).
- Biocompatibility tests in vivo.
Biosensors design
- Bioanalytical systems for food-quality control, medicine, environment.
- Determination of enzymes and metabolites in food-stuffs, blood, microbiological liquids.
Synthesis of organic compounds
- Investigation of synthesis methods for organic compounds of different classes
- Design and development of technology of chemical processes for commerce and industry
Publications
2022
- Aleknavičienė I., E. Pabrėža, M. Talaikis, M. Jankunec, G. Račiukaitis. 2022. Low-cost SERS substrate featuring laser-ablated amorphous nanostructure. Applied Surface Science 571: 151248. IF 6,707
- Ambrulevičius F., G. Valinčius. 2022. Electrochemical impedance spectrum reveals structural details of distribution of pores and defects in supported phospholipid bilayers. Bioelectrochemistry 146: 108092. IF 5.76.
- Belko N., L. Golubewa, V. Chizhevsky, S. Karuseichyk, D. Filimonenko, M. Jankunec, H. Rehman, T. Kulahava, P. Kuzhir, D. Mogilevtsev. 2022. Hysteresis and stochastic fluorescence by aggregated ensembles of graphene quantum dots. Journal of Physical Chemistry C 126(25): 10469-10477. IF 4.177
- Bilvinaitė G., R. Zongolavičiutė, S. Drukteinis, V. Bukelskienė, E. Cotti. 2022. Cytotoxicity and efficacy in debris and smear layer removal of HOCl-based irrigating solution: an In Vitro study. Journal of Functional Biomaterials 13(3): 95. IF 4.901.
- Borutinskaitė V., A.Zučenka, A. Vitkevičienė, M. Stoškus, A. Kaupinis, M. Valius, E. Gineikienė, R. Navakauskienė. 2022. Genetic and epigenetic signatures in acute promyelocytic leukemia treatment and molecular remission. Frontiers in Genetics 13: 821676. IF 4.772
- Budvytytė R., F. Ambrulevičius, E. Jankaitytė, G. Valinčius. 2022. Electrochemical assessment of dielectric damage to phospholipid bilayers by amyloid beta-oligomers. Bioelectrochemistry 145: 108091. IF 5.76
- Chelliah R., E. B.-M. Daliri, I. Khan, S. Wei, F. Elahi, S.-J. Yeon, V. Selvakumar, F.K. Ofosu, M. Rubab, H.H. Ju, H. R. Rallabandi, I. H. Madar, G. Sultan, D.-H.Oh. 2022. A review on the application of bioinformatics tools in food microbiome studies. Briefings in Bioinformatic 23(2): DOI 10.1093/bib/bbac007. IF 13.994
- Cicėnas J., E. Meškinytė-Kausilienė, V. Jukna, A. Rimkus, J. Šimkus, D. Soderholm. 2022. SGK1 in cancer: biomarker and drug target. Cancers 14(10): 2385. IF 6,575
- Čeksterytė V., A. Kaupinis, K. Jaskunė, G. Treigytė, R. Navakauskienė. 2022. Characteristics of honey bee physiological proteins extracted from faba bean (Vicia faba L.) honey. Journal of Apicultural Research DOI 10.1080/00218839.2022.2070099. IF 2.407.
- Dudkaitė V., G. Bagdžiūnas. 2022. Functionalization of glucose oxidase in organic solvent: towards direct electrical communication across enzyme-electrode interface. Biosensors-Basel 12(5): 335. IF 5,743.
- Gabriūnaitė I., G. Valinčius, A. Žilinskas, A. Valiūnienė, 2022. Tethered bilayer membrane formation on silanized fluorine doped tin oxide surface. Journal of the Electrochemical Society 169 (3): 037515 IF 4,371.
- Gaigalas P., T. Sabirovas, I. Matulaitienė, A. Jagminas. 2022. Impact of histidine amino acid on 2D molybdenum disulfide catalytic properties for hydrogen evolution reaction. Journal of Applied Electrochemistry DOI 10.1007/s10800-022-01762-2 IF 2.925.
- Ganpule S., A. K. Vijaya, A. Sukova, G. Preta. 2022. Membrane cholesterol content and lipid organization influence melittin and pneumolysin pore-forming activity. Toxins 14(5): 346. IF 5.075.
- Garcia-Blanco A., L. Domingo-Rodriguez, J. Cabana-Dominguez, N. Fernandez-Castillo, L. Pineda-Cirera, J. Mayneris-Perxachs, A. Burokas, J. Espinosa-Carrasco, S. Arboleya, J. Latorre, C. Stanton, B. Cormand, J.M. Fernandez-Real, E. Martin-Garcia, R. Maldonado. 2022. miRNA signatures associated with vulnerability to food addiction in mice and humans. Journal of Clinical Investigation 132(10): e156281. IF 19,477.
- Gindraux F., N. Hofmann, M. Agudo-Barriuso, M. Antica, P. S. Couto, M. Dubus, S. Forostyak, L. Girandon, R. Gramignoli, M. Jurga, S. Liarte, R. Navakauskienė, V. Shablii, X. Lafarge, F. J.Nicolas, 2022. Perinatal derivatives application: Identifying possibilities for clinical use. Frontiers in Bioengineering and Biotechnology 10: 977590. IF 6.064.
- Han Y., M. King., E. Tikhomirov, P. Barasa, C.D.S. Souza, J. Lindh, D. Baltriukienė, L. Ferraiuolo, M. Azzouz, M.R. Gullo, E. Kozlova. 2022. Towards 3D bioprinted spinal cord organoids. International Journal of Molecular Sciences 23(10): 5788. IF 6.208.
- Imklin N., P. Chaengphaniad, E. Šimoliūnas, R. Nasanit. 2022. A novel Staphylococcus phage, vB_Sau-RP15, and its application in contaminated milk. Letters in Applied Microbiology. DOI 10.1093/lambio/ovac003. IF 2.813.
- Juškauskas A., A. Zajančkauskaitė, R. Meškys, M. Ger, A. Kaupinis, M. Valius, L. Truncaitė. 2022. Interaction between phage T4 protein RIII and host ribosomal protein S1 inhibits endoribonuclease RegB activation. International Journal of Molecular Sciences 23(16): 9483. IF 6,208.
- Koplūnaitė M., K. Butkutė, D. Špelveris, N. Urbelienė, R. Meškys. 2022. Enzymatic synthesis of modified nucleoside 5′-monophosphates. Catalysts 12(11), 1401. IF 4,501
- Kupčinskaitė E., M. Tutkus, A. Kopūstas, S. Ašmontas, M. Jankunec, M. Zaremba, G. Tamulaitienė, T. Šinkūnas. 2022. Disarming of type I-F CRISPR-Cas surveillance complex by anti-CRISPR proteins AcrIF6 and AcrIF9. Scientific Reports 12(1): 15548. IF 4.997.
- Lesanavičius M., J.L. Boucher, N. Čėnas. 2022. Reactions of recombinant neuronal nitric oxide synthase with redox cycling xenobiotics: a mechanistic study. International Journal of Molecular Sciences 23(2): 980. IF 6.208.
- Lesanavičius M., D. Seo, N. Čėnas. 2022. Thioredoxin reductase-type ferredoxin: NADP(+) oxidoreductase of Rhodopseudomonas palustris: potentiometric characteristics and reactions with nonphysiological oxidants. Antioxidants 11(5): 1000. IF 7,675.
- Mayneris-Perxachs J., M. Arnoriaga-Rodriguez, J. Garre-Olmo, J. Puig, R. Ramos, M. Trelis, A. Burokas, C. Coll, C. Zapata-Tona, S. Pedraza, V. Perez -Brocal, L. Ramió, W. Ricart, A. Moya, M. Jove, J. Sol, M. Portero-Otin, R. Pamplona, R. Maldonado, J. M. Fernandez-Real. 2022. Presence of Blastocystis in gut microbiota is associated with cognitive traits and decreased executive function. ISME Journal DOI 10.1038/s41396-022-01262-3 IF 11.217
- Mayneris-Perxachs J., A. Castells-Nobau, M. Arnoriaga-Rodriguez, M. Martin, L. de la Vega-Correa, C. Zapata-Tona, A. Burokas, G. Blasco, C. Coll, A. Escrichs, C. Biarnes, J.M. Moreno-Navarrete, J. Puig, J. Garre-Olmo, R. Ramos, S. Pedraza, R. Brugada, J.C. Vilanova, J. Serena, J. Gich, L. Ramio-Torrenta, V. Perez -Brocal, A. Moya, R. Pamplona, J. Sol, M. Jove, W. Ricart, M. Portero-Otin, G. Deco, R. Maldonado, J. M. Fernandez-Real. 2022. Microbiota alterations in proline metabolism impact depression. Cell Metabolism 34(5): 681+ IF 31.373.
- Mayneris-Perxachs J., A. Castells-Nobau, M. Arnoriaga-Rodriguez, J. Garre-Olmo, J. Puig, R. Ramos, F. Martinez-Hernandez, A. Burokas, C. Coll, J.M. Moreno-Navarrete, C. Zapata-Tona, S. Pedraza, V. Perez -Brocal, L. Ramió-Torrentà, W. Ricart, A. Moya, M. Martinez-Garcia, R. Maldonado, J. M. Fernandez-Real. 2022. Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans. Cell Host & Microbe 30(3) 340+. IF 31.316.
- Makaras T., J. Razumienė, V. Gurevičienė, G. Sauliutė, M. Stankevičiutė. 2022. Technical suitability and reliability of an in vivo and non-invasive biosensor-type glucose assessment as a potential biomarker for multiple stressors in fishes: an evaluation on Salmonids. Environmental Science and Pollution Research 29(27): 41187-41206 IF 5.19
- Megur A., E. B. M. Daliri, D. Baltriukienė, A. Burokas. 2022. Prebiotics as a tool for the prevention and treatment of obesity and diabetes: classification and ability to modulate the gut microbiota. International Journal of Molecular Sciences 23(11): 6097. IF 6.208.
- Misevičienė L., K. Krikštopaitis, N. Čėnas. 2022. The comparative study of redox properties of recombinant human cytosolic and mitochondrial NADPH:thioredoxin reductases. Chemija 33 (2): 40-45. IF 0,636.
- Miškinis J., E. Ramonas, V. Gurevičenė, J. Razumienė, M. Dagys, D. Ratautas. 2022. Capacitance-based biosensor for the measurement of total loss of l-amino acids in human serum during hemodialysis. ACS Sensors DOI 10.1021/acssensors.2c01342 IF 9.618
- Murauskas T., V. Kubilius, M. Talaikis, A. Abrutis, R. Raudonis, G. Niaura, V. Plaušinaitienė. 2022. Precise composition control and cation nonstoichiometry in La-doped BaSnO3 thin films grown by MOCVD. Journal of Alloys and Compounds 898: 162843. IF 6,371.
- Navakauskienė R., S. Baronaitė, D. Matuzevičius, N. Krasovskaja, G. Treigytė, A. Arlauskienė, D. Navakauskas. 2022. Comparative proteomic assessment of normal vs. polyhydramnios amniotic fluid based on computational analysis. Biomedicines 10(8): 1821. IF 4.757.
- Neciporenko A., F. Ivanauskas, J. Dabulytė-Bagdonavičienė, A. Povilaitis, V. Laurinavičius. 2022. Nitrate removal in woodchip denitrification bioreactor - an approach combining mathematical modelling and pi control. Journal of Environmental Engineering and Landscape Management 30(1): 13-21. IF 1,302.
- Ofosu F.K., F. Elahi, E. B-M. Daliri, S.-Ik Han, D.-H Oh. 2022. Impact of thermal treatment and fermentation by lactic acid bacteria on sorghum metabolite changes, their antioxidant and antidiabetic activities. Food Bioscience 45: 101502. IF 5.318
- Pakalniškis A., R. Skaudžius, D.V. Zhaludkevich, S. Latushka, V. Sikolenko, A.V. Sysa, M. Silibin, K. Mažeika, D. Baltrūnas, G. Niaura, M. Talaikis, D. V. Karpinsky, A. Kareiva. 2022. Pressure induced phase transitions in Sm-doped BiFeO3 in the morphotropic phase boundary. Materials Chemistry and Physics 277: 125458. IF 4.778.
- Pakstas V., G. Grinčienė, A. Selskis, S. Balakauskas, M. Talaikis, L. Bruc, N. Curmei, G. Niaura, M. Franckevičius. 2022. Improvement of CZTSSe film quality and superstrate solar cell performance through optimized post-deposition annealing. Scientific Reports 12(1): 16170. IF 4.997
- Petkevičius V., J. Vaitekūnas, M. Sadauskas, F. P. Schultes, D. Tischler, R. Meškys. 2022. The versatility of non-heme diiron monooxygenase PmlABCDEF: a single biocatalyst for a plethora of oxygenation reactions. Catalysis Science & Technology DOI 10.1039/d2cy01167k IF 6,177
- Plakys G., R. Gasparavičiutė, J. Vaitekūnas, R. Rutkienė, R. Meškys. 2022. Characterization of Paenibacillus sp. GKG endo-beta-1, 3-glucanase, a member of family 81 glycoside hydrolases. Microorganisms 10 (10): 1930. IF 4.926
- Polmickaitė-Smirnova E., I. Buchovec, S. Bagdonas, E. Sužiedelienė, A. Ramanavičius, Ž. Anusevičius. 2022. Photoinactivation of Salmonella enterica exposed to 5-aminolevulinic acid: Impact of sensitization conditions and irradiation time. Journal of Photochemistry and Photobiology B-Biology 231: 112446. IF 6,814.
- Pozzobon M., D'Agostino, M.G.G. Roubelakis, A. Cargnoni, R. Gramignoli, S. Wolbank, F. Gindraux, S. Bollini, H. Kerdjoudj, M. Fenelon, R. Di Pietro, M. Basile, V. Borutinskaitė, R. Piva, A. Schoeberlein, G. Eissner, B. Giebel, P. Ponsaerts, 2022. General consensus on multimodal functions and validation analysis of perinatal derivatives for regenerative medicine applications. Frontiers in Bioengineering and Biotechnology 10: 961987. IF 6.064.
- Preta G. 2022. Role of lactone and acid forms in the pleiotropic effects of statins. Pharmaceutics 14(9): 1899. IF 6.525.
- Pudzaitis V., M. Talaikis, R. Sadzevičienė, L. Labanauskas, G. Niaura. 2022. Electrochemical SEIRAS analysis of imidazole-ring-functionalized self-assembled monolayers. Materials 15(20): 7221. IF 3.748.
- Radveikienė I., D. Palinauskas, E. Ragauskaitė, G. Bagdžiūnas. 2022. Self-assembled cyclodextrins-based nanostructures on indium-tin-oxide for a detection of catecholamine neurotransmitters. Applied Surface Science 600: 154170. IF 7.392.
- Raila T., T. Penkauskas, F. Ambrulevičius, M. Jankunec, T. Meškauskas, G. Valinčius.2022. AI-based atomic force microscopy image analysis allows to predict electrochemical impedance spectra of defects in tethered bilayer membranes. Scientific Reports 12(1): 1127. IF 4,997.
- Ramonas E., M. Butkevičius, S. Shleev, M. Dagys, D. Ratautas. 2022. Mechanistic characterization of an oxygen reduction reaction-driven, fully enzymatic and self-calibrating pH biosensor based on wired bilirubin oxidase. Sensors and Actuators B: Chemical 367: 132054. IF 9,221
- Rehman H., L. Golubewa, A. Basharin, A. Urbanovic, E. Lahderanta, E. Soboleva, I. Matulaitienė, M. Jankunec, Y. Svirko, P. Kuzhir, 2022. Fragmented graphene synthesized on a dielectric substrate for THz applications. Nanotechnology 33(39): 395703. IF 3.953
- Rinkūnaitė I., Eg. Šimoliūnas, M. Alksnė, G. Bartkutė, S. Labeit, V. Bukelskienė, J. Bogomolovas. 2022. Genetic ablation of Ankrd1 mitigates cardiac damage during experimental autoimmune myocarditis in mice Biomolecules 12 (12): 1898. IF 6.064.
- Rutkūnas V., R. Borusevičius, E. Balčiūnas, U. Jasinskytė, M. Alksnė, E. Šimoliūnas, S. Zlatev, V. Ivanova, V. Bukelskienė, E. Mijiritsky. 2022. The effect of UV treatment on surface contact angle, fibroblast cytotoxicity, and proliferation with two types of zirconia-based ceramics. International Journal of Environmental Research and Public Health 19(17): 11113. IF 4.614
- Serapinas S., J. Gineitytė, M. Butkevičius, R. Danilevičius, M. Dagys, D. Ratautas. 2022. Biosensor prototype for rapid detection and quantification of DNase activity. Biosensors & Bioelectronics 213: 114475. IF 12.545
- Shafaat A., R. Žalneravičius, D. Ratautas, M. Dagys, R. Meškys, R. Rutkienė, J.F. Gonzalez-Martinez, J. Neilands, S. Bjorklund, J. Sotres, T. Ruzgas. 2022. Glucose-to-resistor transduction integrated into a radio-frequency antenna for chip-less and battery-less wireless sensing. ACS Sensors 7(4): 1222-1234. IF 9,618 Q1D1 Chem anal Q1 chem multid Q1 nanos nanotechn
- Skliutė G., R. Baušytė, D. Ramašauskaitė, R. Navakauskienė. 2022. Characterization of epigenetic and molecular factors in endometrium of females with infertility. Biomedicines 10(6): 1324. IF 4,757
- Statkevičiūtė R., M. Sadauskas, J. Rainytė, K. Kavaliauskaitė, R. Meškys. 2022. Comparative analysis of mesophilic YqfB-type amidohydrolases. Biomolecules 12(10): 1492. IF 6.064
- Šarlauskas J., J. Stankevičiūtė, J. Tamulienė. 2022. An efficient synthesis and preliminary investigation of novel 1,3-dihydro-2h-benzimidazol-2-one nitro and nitramino derivatives Materials 15(23): 8330. IF 3.748
- Šarlauskas J., J. Tamulienė. 2022. Preparation and characterization of cationic energetic salts of 5-amino-3-[(2,4,6-trinitrophenyl)amino]-1H-1,2,4-triazole (APATO). Central European Journal of Energetic Materials 19(3): 311-325 IF 1.104.
- Šarlauskas J., K. Tulaitė, J. Tamulienė. 2022. Investigation of oxygen influence to the optical properties of tirapazamine. Journal of Molecular Modeling 28(4): 96. IF 2,172.
- Tetianec L., I. Bratkovskaja, V. Časaitė, V. Gurevičienė, J. Razumienė, J. Stankevičiūtė, R. Meškys, M. Dagys, A. Laurynėnas. 2022. Efficient bi-enzymatic synthesis of aldonic acids. Green Chemistry 24(12): 4902-4908. IF 11.034.
- Tyagi A., R. Chelliah, E. B.-M. Daliri, G. Sultan, I. H. Madar, N. Kim, U Shabbir, D.-H.Oh. 2023. Antioxidant activities of novel peptides from Limosilactobacillus reuteri fermented brown rice: A combined in vitro and in silico study. Food Chemistry 404: 134747. IF 9.231.
- J. Uebe, Z. Kryževičius, A. Kuhan, A. Torkelis, L. Kosychova, A. Žukauskaitė. 2022. Improving of pyrolysis oil from macroalgae Cladophora glomerata with HDPE pyrolysis oil. Journal of Marine Science and Engineering 10(2): 131. IF 2,744.
- J. Uebe, Z. Kryževičius, R. Majauskienė, M. Dulevičius, L. Kosychova, A. Žukauskaitė. 2022. Use of polypropylene pyrolysis oil in alternative fuel production. Waste Management & Research 0734242X211068243. IF 4.432.
- Vaigauskaitė B., R. Baušytė, E. Valatkaitė, G. Skliutė, E. Kazėnaitė, D. Ramašauskaitė, R. Navakauskienė. 2022. Prognostic gene predictors of gestational diabetes in endometrium and follicular fluid of women after infertility. Medicina-Lithuania 58(4): 498. IF 2,948.
- Vitkevičienė A., G. Skliutė, A. Žučenka, V. Borutinskaitė, R. Navakauskienė. 2022. Potential prognostic markers for relapsed/refractory vs. responsive acute myeloid leukemia. Cancers 14(11): 2752. IF 6,575.
- Zaleskis G., D. Characiejus, J. Juršėnaitė, L. Zibutytė, K. Kriauciunaitė, M. Vanagaitė-Žickienė, A. Darinskas, M. Jonušis, V. Pašukonienė. 2022. Thymus subset alterations accompanying concomitant tumor immunity mimics phenotypic patterns of cytotoxic drug doxorubicin. In Vivo: 36(3): 1106-1113. IF 2.406.
- Zdaniauskienė A., M. Talaikis, T. Charkova. R. Sadzevičienė, L. Labanauskas, G. Niaura. 2022. Electrochemical shell-isolated nanoparticle-enhanced RAMAN spectroscopy of imidazole ring functionalized monolayer on smooth gold electrode. Molecules 27(19): 6531. IF 4.927.
- Zinkevičiūtė R., R. Ražanskas, A. Kaupinis, N. Macijauskaitė, E. Čiplys, G. Houen, R. Slibinskas. 2022. Yeast secretes high amounts of human calreticulin without cellular stress. Current Issues in Molecular Biology 44(5): 1768-1787. IF 2.976.
- Penkauskas T., F. Ambrulevičius, G. Valinčius. 2022. Electrochemical impedance spectroscopy as a convenient tool to characterize tethered bilayer membranes. In: Cranfield, C.G. (eds) Membrane Lipids. Methods in Molecular Biology, vol 2402, pp. 31-59. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1843-1_4
2021
- Aleknavičienė I., M. Jankunec, T. Penkauskas, G. Valinčius. 2021. Electrochemical properties of tethered lipid bilayers on thin film silver substrates. Electrochimica Acta 389: 138726. IF 7,336
- Aleknavičienė I., M. Talaikis, R. Budvytytė, G. Valinčius. 2021. The impact of an anchoring layer on the formation of tethered bilayer lipid membranes on silver substrates. Molecules 26(22): 6878. IF 4,927
- Arnoriaga-Rodriguez M., J. Mayneris-Perxachs, O. Contreras-Rodriguez, A. Burokas, J-A. Ortega-Sanchez, G. Blasco, C. Coll, C. Biarnes, A. Castells-Nobau, J. Puig, J. Garre-Olmo, R. Ramos, S. Pedraza, R. Brugada, J. C. Vilanova, J. Serena, J. Barretina, J. Gich, V. Perez -Brocal, A. Moya, X. Fernandez-Real, L. Ramió-Torrentà, R. Pamplona, J. Sol, M. Jove, W. Ricart, M. Portero-Otin, R. Maldonado, J. M. Fernandez-Real. 2021. Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways. Gut 70(12): 2283-2296. IF 31,793
- Baronas R., J. Kulys, L. Petkevičius. 2021. Modeling carbohydrates oxidation by oxygen catalyzed by bienzyme glucose dehydrogenase/laccase system immobilized into microreactor with carbon nanotubes. Journal of Mathematical Chemistry 59: 168-185. IF 2,413
- Bartusevičienė I., V. Vicka, A. Vickienė, L. Tetianec, M. Dagys, D. Ringaitienė, A. Klimašauskas, J. Šipylaitė. 2021. Conceptual model of adding antibiotics to dialysate fluid during renal replacement therapy. Scientific Reports 11(1): 23836. IF 4,996
- Budvytytė R., A. Milašiutė, D. Vitkus, K. Strupas, A. Gulla, I. Šakinytė, J. Razumienė. 2021. Tethered lipid membranes as a nanoscale arrangement towards non-invasive analysis of acute pancreatitis. Biomedicines 9(7): 755. IF 4,757
- Čeksterytė V., G. Treigytė, D. Matuzevičius, K. Jaškūnė, D. Navakauskas, B. Kurtinaitienė, R. Navakauskienė. 2021. Comparative proteomic profile in bee- and manually-collected Taraxacum officinale pollen. Journal of Apicultural Research doi 10.1080/00218839.2021.1969819 IF 2.407
- Čėnas N., A. Nemeikaitė-Čėnienė, L. Kosychova. 2021. Single- and two-electron reduction of nitroaromatic compounds by flavoenzymes: mechanisms and implications for cytotoxicity. International Journal of Molecular Sciences 22 (16): 8534 IF 6,208
- Cicėnas J., A. Račienė. 2021. Anti-cancer drugs targeting protein kinases approved by FDA in 2020. Cancers 13(5), 947 IF 6.575
- Cichocki B. A, M. Donzel, K. C. Heimsch, M.Lesanavičius, L. Feng, E.J. Montagut, K. Becker, A.Aliverti, M. Elhabiri, N. Čėnas, E. Davioud-Charvet. 2021. Plasmodium falciparum ferredoxin-NADP+ reductase-catalyzed redox cycling of plasmodione generates both predicted key drug metabolites: implication for antimalarial drug development. Infectious Diseases 7(7) 1996-2012. IF 5,578
- Čiplys E., T. Paškevičius, E. Žitkus, J. Bielskis, R. Ražanskas, T. Sneideris, V. Smirnovas, A. Kaupinis, D. Tester, M. Ackerman, P. Hojrup, M. Michalak, G. Houen, R. Slibinskas. 2021. Mapping human calreticulin regions important for structural stability. Biochimica et Biophysica Acta-Proteins and Proteomics 1869(11): 140710. IF 4,125
- Daublytė E., A. Zdaniauskienė, M. Talaikis, A. Drabavičius, T. Charkova. 2021. A facile microwave-assisted synthesis of Ag@SiO2 nanoparticles for Raman spectroscopy. New Journal of Chemistry 45(24): 10952-20958. IF 3,925
- Gabriūnaitė I., A. Valiūlienė, T. Sabirovas, G. Valinčius. 2021. Mixed silane-based self-assembled monolayers deposited on fluorine doped tin oxide as model system for development of biosensors for toxin detection. Electroanalysis 33(5): 1315-1324. IF 3,077
- Garofalo T., R. Misasi, G. Preta. 2021. Editorial: targeting lipid rafts as a strategy against infection and cancer. Frontiers in Cell and Developmental Biology 9: 748905. IF 6,081
- Gendvilienė I., Eg. Šimoliūnas, M. Alksnė, S. Dibart, E. Jasiūnienė, V. Cicėnas, R. Jacobs, V. Bukelskienė, V. Rutkūnas. 2021. Effect of extracellular matrix and dental pulp stem cells on bone regeneration with 3D printed PLA/HA composite scaffolds. European Cells & Materials 41: 204-215. IF 4,325
- Golovinas E., D. Rutkauskas, E. Manakova, M. Jankunec, A. Silanskas, G. Sasnauskas, M. Zaremba. 2021. Prokaryotic Argonaute from Archaeoglobus fulgidus interacts with DNA as a homodimer. Scientific Reports 11(1) 4518. IF 4,996
- Grybauskaitė-Kaminskienė G., V. Dudkaitė, G. Bagdžiūnas. 2021. Photophysical and semiconducting properties of isomeric triphenylimidazole derivatives with a benzophenone moiety. New Journal of Chemistry 45(42): 19746-19754. IF 3,925
- Javorskis T., A. Jurys, G. Bagdžiūnas, E. Orentas. 2021. Synthesis of C- and N-substituted 1,5,2,6-dithiadiazocanes -electrophilic-nucleophilic thioamination (ENTA) reagents. Advanced Synthesis & Catalysis 363(13): 3329-3335. IF 5.981
- Jelmakas E., A. Kadys, M. Dmukauskas, T.Grinys, R. Tomasiunas, D. Dobrovolskas, G. Gervinskas, S. Juodkazis, M. Talaikis, G. Niaura. 2021. FIB micro-milled sapphire for GaN maskless epitaxial lateral overgrowth: a systematic study on patterning geometry. Journal of Materials Science-Materials in Electronics 32(11): 14532-14541. IF 2,779
- Kalinienė L., A. Noreika, A. Kaupinis, M. Valius, E. Jurgelaitis, J. Lazutka, R. Meškienė, R. Meškys. 2021. Analysis of a novel bacteriophage vB_AchrS_AchV4 highlights the diversity of Achromobacter viruses. Viruses 13(3): 374. IF 5,818
- Karoblis D., R. Diliautas, K. Mažeika, D. Baltrūnas, G. Niaura, M. Talaikis, A. Beganskienė, A. Zarkov, A. Kareiva. 2021. Lanthanum and manganese co-doping effects on structural, morphological, and magnetic properties of sol-gel derived BiFeO3. Materials 14(17): 4844. IF 3,748
- Kažukauskienė I., V. Baltrūnienė, I. Rinkūnaitė, E. Žurauskas, D. Vitkus, V. V. Maneikienė, K. Ručinskas, V. Grabauskienė. 2021. Inflammation-related biomarkers are associated with heart failure severity and poor clinical outcomes in patients with non-ischemic dilated cardiomyopathy. Life 11(10): 1006. IF 3,251
- Krikštaponis A., G. Urbelis, R. Meškys. 2021. The first step of biodegradation of 7-hydroxycoumarin in Pseudomonas mandelii 7HK4 depends on an alcohol dehydrogenase-type enzyme. International Journal of Molecular Sciences. 22(4): 1552. IF 6,208
- Kurlinkus B., M. Ger, A. Kaupinis, E. Jasiūnas, M. Valius, A. Šileikis. 2021. CEACAM6’s role as a chemoresistance and prognostic biomarker for pancreatic cancer: a comparison of CEACAM6’s diagnostic and prognostic capabilities with those of CA19-9 and CEA. Life 11(6): 542. IF 3,251
- Labutytė G., S. Povilonienė, E. Šimoliūnas, D. Gabrielaitis, M. Skapas, A. Noreika, R. Meškys, V. Časaitė. 2021. Functionalized protein nnotubes based on the bacteriophage vB_KleM-RaK2 tail sheath protein. Nanomaterials 11(11): 3031. IF 5.719
- Lastauskienė E., V. Valskys, J. Stankevičiūtė, V. Kalcienė, V. Gėgžna, J. Kavoliunas, M. Ružauskas, J. Armalytė. 2021. TThe impact of intensive fish farming on pond sediment microbiome and antibiotic resistance gene composition.Frontiers in Veterinary Science 8: 673756 IF 3,471
- Linklater E. S., E. D. Duncan, Ke-Jun Han, A. Kaupinis, M. Valius, T.R. Lyons, R. Prekeris. 2021. Rab40–Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration. Journal of Cell Biology 220(7): e202008060. IF 8,077
- Liustrovaitė V., A. Valiūnienė, G. Valinčius, A. Ramanavičius. 2021. Electrochemical Impedance Spectroscopy Based Evaluation of Chlorophyll a Reconstitution within Tethered Bilayer Lipid Membrane. Journal of the Electrochemical Society 168 (6): 066506. IF 4,386
- Makaras T., M. Stankevičiūtė, E. Šidagytė-Copilas, T. Virbickas, J. Razumienė. 2021. Acclimation effect on fish behavioural characteristics: determination of appropriate acclimation period for different species. Journal of Fish Biology 99(2): 502-512. IF 2,504
- A. Megur, D. Baltriukienė, V. Bukelskienė, A. Burokas. 2021. The microbiota-gut-brain axis and Alzheimer's disease: neuroinflammation is to blame? Nutrients. 13(1) 37. IF 6,706
- Nemeikaitė-Čėnienė A., A. Marozienė, L. Misevičienė, J. Tamulienė, A. Yantsevich, N. Čėnas. 2021. 5Flavoenzyme-catalyzed single-electron reduction of nitroaromatic antiandrogens: implications for their cytotoxicity. Free Radical Research 55(3): 246-254. IF 4.354
- Olejarczyk E., A. Jozwik, V. Valiulis, K. Dapšys, G. Gerulskis, A. Germanavičius. 2021. Statistical analysis of graph-theoretic indices to study EEG-TMS connectivity in patients with depression. Frontiers in Neuroinformatics 15: 651082. IF 3,739
- Olejarczyk E., V. Valiulis, K. Dapšys, G. Gerulskis, A. Germanavičius. 2021. Effect of repetitive transcranial magnetic stimulation on fronto-posterior and hemispheric asymmetry in depression. Biomedical Signal Processing and Control 68: 102585. IF 5,076
- Petkevičius V., J. Vaitekūnas, R. Gasparavičiūtė, D. Tauraitė, R. Meškys. 2021. An efficient and regioselective biocatalytic synthesis of aromatic N-oxides by using a soluble di-iron monooxygenase PmlABCDEF produced in the Pseudomonas species. Microbial Biotechnology 14(4): 1771-1783. IF 6,575
- Pezze L., E. Meškytė, M. Forcato, S.Pontalti, K. Badowska, D. Rizzotto, I.I. Skvortsova, S. Bicciato, Y. Ciribilli. 2021. ETV7 regulates breast cancer stem-like cell features by repressing IFN-response genes. Cell Death & Disease 12(8): 742 IF 9,685.
- Pranckūnas M., Eg. Šimoliūnas, M. Alksnė, V. Martin, P.S. Gomes, A. Puišys, A. Kaupinis, G. Juodžbalys. 2021. Assessment of the bone healing process mediated by periosteum-derived mesenchymal stem cells' secretome and a xenogenic bioceramic-an in vivo study in the rabbit critical size calvarial defect model. Materials 14(13): 3512. IF 3,748
- Radveikienė I., R. Vidžiūnaitė, R. Meškienė, R. Meškys, V. Časaitė. 2021. Characterization of a yellow laccase from Botrytis cinerea 241. Journal of Fungi 7(2): 143. IF 5,724
- Ramonas E., A. Shafaat, M. Dagys, T. Ruzgas, D. Ratautas. 2021. Revising catalytic "acceleration" of enzymes on citrate-capped gold nanoparticles. Journal of Catalysis 404: 570-578. IF 8.047
- Repečka D., V. Jauniškis, L. Karpus, E. Rembeza, I. Rokaitis, J. Zrimec, S. Povilonienė, A. Laurynėnas, S. Viknander, W. Abuajwa, O. Savolainen, R. Meškys, M. K. M. Engqvist, A. Zelezniak. 2021. Expanding functional protein sequence spaces using generative adversarial networks. Nature Machine Intelligence 3(4): 324-333. IF 25.898
- Rinkūnaitė I., Eg. Šimoliūnas, M. Alksnė, D. Dapkutė, V. Bukelskienė. 2021. Anti-inflammatory effect of different curcumin preparations on adjuvant-induced arthritis in rats. BMC Complementary Medicine and Therapies 21 (1): 39. IF 2.838
- Rinkūnaitė I., Eg. Šimoliūnas, D. Bironaitė, R. Rutkienė, V. Bukelskienė, R. Meškys, J. Bogomolovas. 2021. The effect of a unique region of Parvovirus B19 capsid protein VP1 on endothelial cells. Biomolecules 11 (4):606. IF 6,064
- Sabirovas T., A. Valiūnienė, G. Valinčius. 2021. Hybrid bilayer membranes on metallurgical polished aluminum. Scientific Reports 11(1): 9648. IF 4,996
- Savickaitė A., G. Druteika, M. Sadauskas, V. Malunavičius, E. Lastauskienė, R. Gudiukaitė. 2021. Immobilized GDEst-95, GDEst-lip and GD-95RM lipolytic enzymes for continuous flow hydrolysis and transesterification reactions. International Journal of Biological Macromolecules 168: 261-271. IF 8,025
- Savickaitė A., M. Sadauskas, R. Gudiukaitė. 2021. Study of individual domains' functionality in fused lipolytic biocatalysts based on Geobacillus lipases and esterases. International Journal of Biological Macromolecules 173: 421-434. IF 8,025
- Skliutė G., R. Baušytė, V.V. Borutinskaitė, G. Valiulienė, A. Kaupinis, M. Valius, D. Ramašauskaitė, R. Navakauskienė. 2021. Menstrual blood-derived endometrial stem cells' impact for the treatment perspective of female infertility. International Journal of Molecular Sciences 22(13): 6774. IF 6,208
- Stulpinas A., T. Užusienis, A. Imbrasaitė, N. Krestnikova, A. Ungurytė, A.V. Kalvelytė. 2021. Cell-cell and cell-substratum contacts in the regulation of MAPK and Akt signalling: Importance in therapy, biopharmacy and bioproduction. Cellular Signalling 84: 110034 IF 4,850
- Šakinytė I., M. Butkevičius, V. Gurevičienė, J. Stankevičiūtė, R. Meškys, J. Razumienė.2021. Reagentless D-tagatose biosensors based on the oriented immobilization of fructose dehydrogenase onto coated gold nanoparticles- or reduced graphene oxide-modified surfaces: application in a prototype bioreactor. Biosensors-Basel 11(11): 466. IF 5,743
- Šarlauskas J., J. Tamulienė, S. Bekešienė, A. Kravcov. 2021. Benzimidazole derivatives as energetic materials: A theoretical study. Materials 14 (15): 4112. IF 3,748
- Šimoliūnas Eg., I. Ivanauskienė, L. Bagdzevičiūtė, I. Rinkūnaitė, M. Alksnė, D. Baltriukienė. 2021. Surface stiffness depended gingival mesenchymal stem cell sensitivity to oxidative stress. Free Radical Biology and Medicine 169: 62-73. IF 8.101
- Šimoliūnas Eg., P. Kantakevičius, M. Kalvaitytė, L. Bagdzevičiūtė, M. Alksnė, D. Baltriukienė . 2021. DNA-DAPI interaction-based method for cell proliferation rate evaluation in 3D structures. Current Issues in Molecular Biology 43(1) 251-263. IF 2,976
- Šimoliūnienė M., D. Kazlauskas, A. Zajančkauskaitė, R. Meškys L.Truncaitė. 2021. Escherichia coli trxA gene as a molecular marker for genome engineering of felixounoviruses. Biochimica et Biophysica Acta-General Subjects 1865(10): 129967. IF 4,117
- Šimoliūnienė M., E. Žukauskienė, L.Truncaitė, L. Cui, G. Hutinet, D. Kazlauskas, A. Kaupinis, M. Skapas, V.d. Crécy-Lagard, P.C.Dedon, M. Valius, R. Meškys, E. Šimoliūnas. 2021. Pantoea bacteriophage vB_PagS_MED16—A siphovirus containing a 2′-deoxy-7-amido-7-deazaguanosine-modified DNA. International Journal of Molecular Sciences 22: 7333. IF 6,208
- Šulčius S., G. Alzbutas, V. Juknevičiūtė, E. Šimoliūnas, P. Venckus, M. Šimoliūnienė, R. Paškauskas. 2021. Exploring viral diversity in a gypsum karst lake ecosystem using targeted single-cell genomics. Genes 12(6): 886. IF 4.141
- Teišerskytė V., J. Urbonavičius, D. Ratautas. 2021. A direct electron transfer formaldehyde dehydrogenase biosensor for the determination of formaldehyde in river water. Talanta 234: 122657. IF 6.581 .
- Valatkaitė E., R. Baušytė, A. Vitkevičienė, D. Ramašauskaitė, R. Navakauskienė. 2021. Decidualization potency and epigenetic changes in human endometrial origin stem cells during propagation. Frontiers in Cell and Developmental Biology 9: 765265. IF 6,081 .
- Valiulienė G., V. Valiulis, K. Dapšys, A. Vitkevičienė, G. Gerulskis, R. Navakauskienė, A. Germanavičius. 2021. Brain stimulation effects on serum BDNF, VEGF, and TNF alpha in treatment-resistant psychiatric disorders. European Journal of Neuroscience 53(11): 3791-3802. IF 3,698
- Valiulienė G., A. Vitkevičienė, G. Skliutė, V.V. Borutinskaitė, R. Navakauskienė. 2021. Pharmaceutical drug metformin and MCL1 inhibitor S63845 exhibit anticancer activity in myeloid leukemia cells via redox remodeling. Molecules 26(8): 2303. IF 4,927
- Valiulienė G., A. Zentelytė, E. Beržanskytė, R. Navakauskienė. 2021. Metabolic profile and neurogenic potential of human amniotic fluid stem cells from normal vs. fetus-affected gestations. Frontiers in Cell and Developmental Biology 9: 700634. IF 6,081
- Voitechovic E., J. Stankevičiūtė, A.Vektarienė, G. Vektaris, R. Jančienė, N. Kuisienė, J. Razumienė, R. Meškys. 2021. Bioamperometric systems with fructose dehydrogenase from Gluconobacter japonicus for D-tagatose. Electroanalysis 33(6): 1393-1397. IF 3,077
- Voronovic E., A. Skripka, G. Jarockytė, M. Ger, D. Kučiauskas, A. Kaupinis, M. Valius, R. Rotomskis, F. Vetrone, V. Karabanovas. 2021. Uptake of upconverting nanoparticles by breast cancer cells: surface coating versus the protein corona ACS Applied Materials & Interfaces 13(33): 39076-39087 IF 10,383
- Zajančkauskaitė A., A. Noreika, R. Rutkienė, R. Meškys, L. Kalinienė. 2021. Low-temperature virus vB_EcoM_VR26 shows potential in biocontrol of STEC O26:H11. Foods 10(7): 1500. IF 5.561
- Zaleskis G., S. Garberytė, B. Pavliukevicienė, J. Krasko, M. Skapas, M. Talaikis, A. Darinskas, L. Zibutyte, V. Pašukonienė. 2021. Comparative evaluation of cellular uptake of free and liposomal doxorubicin following short term exposure. Anticancer Research 41(5): 2363-2370. IF 2,435
- Zentelytė A., D. Žukauskaitė, I. Jačerytė, V.V. Borutinskaitė, R. Navakauskienė. 20201. Small molecule treatments improve differentiation potential of human amniotic fluid stem cells. Frontiers in Bioengineering and Biotechnology 9, 623886. IF 6,064
- Zhou J., L. Pecqueur, A. Aučynaitė, J. Fuchs, R. Rutkienė, J. Vaitekūnas, R. Meškys, M. Boll, M. Fontecave, J. Urbonavičius, B. Golinelli-Pimpaneau. 2021. Structural evidence for a [4Fe‐5S] intermediate in the non‐redox desulfuration of thiouracil. Angewandte Chemie International Edition 60: 424-431 IF 16,823
- Zilius M., A. Samuilovienė, R. Stanislauskienė, E. Broman, S. Bonaglia, R. Meškys, A. Zaiko. 2021. Depicting temporal, functional and phylogenetic patterns in estuarine diazotrophic communities from environmental DNA and RNA. Microbial Ecology 81: 36-51.IF 4,192
- Žalytė E., V. Dedonytė, B. Kurlinkus, A. Šileikis, P. Schemmer, M. Valius. 2021. Establishment and characterization of a new pancreatic ductal adenocarcinomacell line Capan-26. Anticancer Research 41(3): 1401-1406. IF 2,435
- Žukauskienė E., M. Šimoliūnienė, L. Truncaitė, M. Skapas, A. Kaupinis, M. Valius, R. Meškys, E. Šimoliūnas. 2021. Pantoea bacteriophage vB_PagS_AAS23: a singleton of the Genus Sauletekiovirus. Microorganisms 9(3): 668. IF 4.926
- Navakauskienė Rūta, Navakauskas Dalius, Borutinskaitė Veronika Viktorija, Matuzevičius Dalius. Epigenetics and proteomics of leukemia. A synergy of experimental biology and computational informatics. Springer, 2021. 406 p. ISBN 9783030687076
- Baronas Romas, Ivanauskas Feliksas, Kulys Juozas. Mathematical modeling of biosensors. Second edition. Springer, 2021. 473 p. Springer Series on Chemical Sensors and Biosensors, vol. 9. ISBN 9783030655044.
2020
- Alksnė M., M. Kalvaitytė, E. Šimoliūnas, I. Rinkūnaitė, I. Gendvilienė, J. Locs, V. Rutkūnas, V. Bukelskienė. 2020. In vitro comparison of 3D printed polylactic acid/hydroxyapatite and polylactic acid/bioglass composite scaffolds: Insights into materials for bone regeneration. Journal of the Mechanical Behavior of Biomedical Materials 104: 103641. IF 3.902
- Arnoriaga-Rodriguez M., J. Mayneris-Perxachs, A. Burokas, O. Contreras-Rodriguez, G. Blasco, C. Coll, C. Biarnes, R. Miranda-Olivos, J. Latorre, J.M. Moreno-Navarrete, A. Castells-Nobau, M. Sabater, M. E. Palomo-Buitrago, J. Puig, S. Pedraza, J. Gich, V. Perez-Brocal, W. Ricart, A. Moya, X. Fernandez-Real, L. Ramió-Torrentà, R. Pamplona, J. Sol, M. Jove, M. Portero-Otin, R. Maldonado, J. M. Fernandez-Real. 2020. Obesity impairs short-term nd working memory through gut microbial metabolism of aromatic amino acids. Cell Metabolism 32: 548-560. IF 27,287
- Arnoriaga-Rodriguez M., J. Mayneris-Perxachs, A. Burokas, V. Perez-Brocal, A. Moya, M. Portero-Otin, W. Ricart, R. Maldonado, J.M. Fernandez-Real. 2020. Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile. Microbiome 8: AN 59. IF 14.65
- Bagdžiūnas G. 2020 Theoretical design of molecularly imprinted polymers based on polyaniline and polypyrrole for detection of tryptophan. Molecular Systems Design & Engineering 5: 1504-1512. IF 4.932
- Bagdžiūnas G.,, D. Palinauskas. 2020. Poly(9H-carbazole) as a organic semiconductor for enzymatic and non-enzymatic glucose sensors. Biosensors-Basel 10(8): AN 104. IF 5.519
- Bagdžiūnas G., D. Palinauskas, A. Ramanavičius. 2020. Towards colourless‐to‐green electrochromic smart glass based on a redox active polymeric semiconductor containing carbazole moiety. Dyes and Pigments 177: 108328. IF 4.889
- Baltrūnienė V., I. Rinkūnaitė, J. Bogomolovas, D. Bironaitė, I. Kažukauskienė, E. Šimoliūnas, K. Ručinskas, R. Puronaitė, V. Bukelskienė, A.V. Grabauskienė. 2020. The role of cardiac T-cadherin in the indicating heart failure severity of patients with non-ischemic dilated cardiomyopathy. Medicina-Lithuania 56: 27. IF 2.43
- Benitez D., M. A. Comini, Ž. Anusevičius, J. Šarlauskas, V. Miliukienė, E. Miliuvienė, N. Čėnas. 2020. 5-Vinylquinoline-substituted nitrofurans as inhibitors of trypanothione reductase and antitrypanosomal agents. Chemija 31: 111-117. IF 0,635.
- Časaitė V., R. Stanislauskienė, J. Vaitekūnas, D. Tauraitė, R. Rutkienė, R. Gasparavičiūtė, R. Meškys. 2020. Microbial degradation of pyridine: a complete pathway deciphered in Arthrobacter sp. 68b. Applied and Environmental Microbiology 86(15): e00902-20. IF 4.792
- Čeksterytė V., B. Kurtinaitienė, K. Jaskūnė, J. Kretavičius. 2020. The influence of storage conditions on invertase, glucose oxidase activity and free acidity of bee bread and bee-collected pollen mixed with honey and vegetable oils. Journal of Apicultural Research 59: 862-875. IF 2.584
- Druteika G., M. Sadauskas, V. Malūnavičius, E. Lastauskienė, L. Taujenis, A. Gegeckas, R. Gudiukaitė. 2019. Development of a new Geobacillus lipase variant GDlip43 via directed evolution leading to identification of new activity-regulating amino acids. International Journal of Biological Macromolecules 151: 1194-1204 IF 6.953
- Druteika G., M. Sadauskas, V. Malūnavičius, E. Lastauskienė, R. Statkevičiūtė, A. Savickaitė, R. Gudiukaitė. 2020. New engineered Geobacillus lipase GD-95RM for industry focusing on the cleaner production of fatty esters and household washing product formulations. World Journal of Microbiology&Biotechnology 36(3): 41. IF 3.312
- Gasiūnienė M., E. Valatkaitė, A. Navakauskaitė, R. Navakauskienė. 2020. Long-term cultivation of human amniotic fluid stem cells: The impact on proliferative capacity and differentiation potential. International Journal of Molecular Sciences 21(22): 8752. IF 5.923
- Gasiūnienė M., E. Valatkaitė, R. Navakauskienė. 2020. Long-term cultivation of human amniotic fluid stem cells: The impact on proliferative capacity and differentiation potential. Journal of Cellular Biochemistry 21: 3491-3501. IF 4.429
- Gendvilienė I., E. Šimoliūnas, S. Rekstytė, M. Malinauskas, L. Zaleckas, D. Jegelevičius, V. Bukelskienė, V. Rutkūnas. 2020. Assessment of the morphology and dimensional accuracy of 3D printed PLA and PLA/HAp scaffolds. Journal of the Mechanical Behavior of Biomedical Materials 104:103616. IF 3,902
- Golubewa L., H. Rehman, T. Kulahava, R. Karpicz, M. Baah, T. Kaplas, A. Shah, S. Malykhin, A. Obraztsov, D. Rutkauskas, M. Jankunec, I. Matulaitienė, A. Selskis, A. Denisov, Y. Svirko, P. Kuzhir. 2020. Macro-, micro- and nano-roughness of carbon-based interface with the living cells: towards a versatile bio-sensing platform. Sensors 20(18): AN 5028. IF 3.576
- Grigalevičiūtė G., D. Baltriukienė, V. Bukelskienė, M. Malinauskas. 2020. Biocompatibility evaluation and enhancement of elastomeric coatings made using table-top optical 3D printer. Coatings 10(3): 254. IF 2.881
- Gružauskaitė J., J. Jasinskaitė, R. Meškys, G. Gaidamavičienė, A. Žalga, A. Laurynėnas, L. Tetianec, M. Dagys. 2020. Gold-coated magnetic nanocatalyst containing wired oxidoreductases for mediatorless catalysis of carbohydrate oxidation by oxygen. Catalysis Communications 135: AN 105848 IF 3.626
- Gudlevičienė Ž., K. Žilinskas, G. Kundrotas, M. Grubliauskaitė, D. Baltriukienė, V. Bukelskienė. 2020. Slow-freezing cryopreservation ensures high ovarian tissue quality followed by in vivo and in vitro methods and is safe for fertility preservation. Medicina-Lithuania 56(10): 547. IF 2.43
- Han Y., D. Baltriukienė, E. Kozlova. 2020. Effect of scaffold properties on adhesion and maintenance of boundary cap neural crest stem cells in vitro. Journal of Biomedical Materials Research Part A. 108: 1274-1280. IF 4.396
- Koplūnaitė M., K. Butkutė, R. Meškys, D. Tauraitė. 2020. Synthesis of pyrimidine nucleoside and amino acid conjugates. Tetrahedron Letters 61(49): AN 152598. IF 2.415
- Kumar A., R. Gudiukaitė, A. Gricajeva, M. Sadauskas, V. Malunavičius, H. Kamyab, S. Sharma, T. Sharma, D. Pant. 2020. Microbial lipolytic enzymes - promising energy-efficient biocatalysts in bioremediation. Energy 192: 116674. IF 7,147
- Kuznecova J., S. Šulčius, A. Vogts, M. Voss, K. Jürgens, E. Šimoliūnas. 2020. Nitrogen flow in diazotrophic cyanobacterium aphanizomenon flos-aquae is altered by cyanophage infection. Frontiers in Microbiology. 11: AN 2010.IF 5,639
- Leonavičienė G., K. Leonavičius, R. Meškys, L. Mažutis. 2020. Multi-step processing of single cells using semi-permeable capsules. Lab on a Chip 20 (21): 4052-4062. IF 6,799
- Lesanavičius M., A. Aliverti, J. Šarlauskas, N. Čėnas. 2020. Reactions of Plasmodium falciparum Ferredoxin:NADP+ Oxidoreductase with Redox Cycling Xenobiotics: A Mechanistic Study. International Journal of Molecular Sciences 21:3234. IF 5,923
- Lučiūnaitė A., R.M McManus, M. Jankunec, I. Racz, C. Dansokho I. Dalgedienė, S. Schwartz, F. Brosseron, M.T. Heneka. 2020. Soluble A beta oligomers and protofibrils induce NLRP3 inflammasome activation in microglia. Journal of Neurochemistry. Article Number: UNSP e14945 IF 4,066
- Mayneris-Perxachs J., M. Arnoriaga-Rodriguez, D. Luque-Cordoba, F. Priego-Capote, V. Perez-Brocal, A. Moya, A. Burokas, R. Maldonado, J. M. Fernandez-Real. 2020. Gut microbiota steroid sexual dimorphism and its impact on gonadal steroids: influences of obesity and menopausal status. Microbiome 8: AN 136. IF 14,65
- Makaras T., J. Razumienė, V. Gurevičienė, I. Šakinytė, M. Stankevičiūtė, N. Kazlauskienė. 2020. A new approach of stress evaluation in fish using β-d-Glucose measurement in fish holding-water. Ecological Indicators 109: 105829. IF 4.958
- Maminskas J., J. Pilipavičius, E. Staisiūnas, G. Baranovas, M. Alksnė, P. Daugėla, G. Juodžbalys. 2020. Novel yttria-stabilized zirconium oxide and lithium disilicate coatings on titanium alloy substrate for implant abutments and biomedical applicationn. Materials 13: AN 2070. IF 3,623
- Meškytė E., S. Keskas, Y. Ciribilli. 2020. MYC as a multifaceted regulator of tumor microenvironment leading to metastasis. International Journal of Molecular Sciences 21:3234. IF 5,923
- Nemeikaitė-Čėnienė, J. Šarlauskas, V. Jonušienė, L. Misevičienė, A. Marozienė, A. Yantsevich, N. Čėnas. 2020. QSARs in prooxidant mammalian cell cytotoxicity of nitroaromatic compounds: the roles of compound lipophilicity and cytochrome P-450- and DT-diaphorase-catalyzed reactions. Chemija 31: 170-177. IF 0,635
- Nemeikaitė-Čėnienė, J. Šarlauskas, L. Misevičienė, A. Marozienė, V. Jonušienė, M. Lesanavičius, N. Čėnas. 2020. Aerobic cytotoxicity of aromatic N-oxides: the role of NAD(P)H:quinone oxidoreductase (NQO1). International Journal of Molecular Sciences 21:8754. IF 5,923
- Noreika A., R. Meškys, J. Lazutka, L. Kalinienė. 2020. Complete genome sequence of Buttiauxellaphage vB_ButM_GuL6. Archives of Virology D166(11): 2685-2687. IF 2,574
- Pampuschenko K., R. Morkūnienė, T. Šneideris, V. Smirnovas, R. Budvytytė, G. Valinčius,GC Brown, V. Borutaitė. 2020. Extracellular tau induces microglial phagocytosis of living neurons in cell cultures. Journal of Neurochemistry 154(3): 316-329. IF 4,066
- Penkauskas T., A. Zentelytė, S. Ganpule, G. Valinčius, G. Preta. 2020. Pleiotropic effects of statins via interaction with the lipid bilayer: A combined approach. Biochimica et Biophysica Acta (BBA) – Biomembranes 1862: 183306. IF 3.747
- Peterman E., M. Valius, R. Prekeris. 2020. CLIC4 is a cytokinetic cleavage furrow protein that regulates cortical cytoskeleton stability during cell division. Journal of Cell Science 133: AN jcs241117. IF 5,285
- Polmickaitė-Smirnova E., J. Šarlauskas, K. Krikštopaitis, Ž. Lukšienė, Z. Staniulytė, Ž. Anusevičius. 2020. Preliminary investigation of the antibacterial activity of antitumor drug 3-amino-1,2,4-benzotriazine-1,4-dioxide (tirapazamine) and its derivatives. Applied Sciences 10: 4062. IF 2.679
- Preta G. 2020. New insights into targeting membrane lipids for cancer therapy. Frontiers in Cell and Developmental Biology 8: AN 571237. IF 6.684
- Radveikienė I., I. Pilotaitė, R. Dainytė, R. Vidžiūnaitė. 2020. Biosynthesis, purification, characterization and immobilization of laccase from Lithothelium sp. Chemija 31: 178-190. IF 0,635
- Raila T., F. Ambrulevičius, T. Penkauskas, M. Jankunec, T. Meškauskas, D. J. Vanderah, G. Valinčius. 2020. Clusters of protein pores in phospholipid bilayer membranes can be identified and characterized by electrochemical impedance spectroscopy. Electrochimica Acta 364: 137179 IF 6.901
- Ramašauskas L., R. Meškys, D. Ratautas. 2020. Real-time glucose monitoring system containing enzymatic sensor and enzymatic reference electrodes. Biosensors and Bioelectronics 164: 112338. IF 10.618
- Ratautas D., M. Dagys. 2020. Nanocatalysts containing direct electron transfer-capable oxidoreductases: recent advances and applications. Catalysts 10: 9. IF 4.146
- Razumienė J., V. Gurevičienė, I. Šakinytė, L. Rimsevičius, V. Laurinavičius. 2020. The synergy of thermally reduced graphene oxide in amperometric urea biosensor: application for medical technologies. Sensors 20: AN 4496. IF 3.576
- E. Ros, M. Reig, C.Voz, G. Bagdžiūnas, P. Ortega, D. Velasco, J. Puigdollers. 2020. Shedding light on the negative differential resistance effect observed in organic thin-film transistors. ACS Applied Electronic Materials 2: 1574-1582. IF 3.314
- Rutkūnas V., R. Borusevičius, D. Liaudanskaitė, U. Jašinskytė, S. Drukteinis, V. Bukelskienė, E. Mijiritsky. 2020. The effect of different cleaning protocols of polymer-based prosthetic materials on the behavior of human gingival fibroblasts. International Journal of Environmental Research and Public Health. 17 (21) AN 7753. IF 3.39
- Sabirovas T., A. Valiūnienė, I. Gabriūnaitė, G. Valinčius. 2020. Mixed hybrid bilayer lipid membranes on mechanically polished titanium surface. Biochimica et Biophysica Acta (BBA) – Biomembranes 1862: 183232. IF 3.747
- Sadauskas M., R. Statkevičiūtė, J. Vaitekūnas, V. Petkevičius, V. Časaitė, R. Gasparavičiūtė, R. Meškys. 2020. Enzymatic synthesis of novel water-soluble indigoid compounds. Dyes and Pigments 173: AN 107882 IF 4.889
- Sadauskas M., R. Statkevičiūtė, J. Vaitekūnas, R. Meškys. 2020. Bioconversion of Biologically Active Indole Derivatives with Indole-3-Acetic Acid-Degrading Enzymes from Caballeronia glathei DSM50014. Biomolecules 10: 663 IF 4.879
- Silini A.R., R. Di Pietro, I. Lang-Olip, F. Alviano, A. Banerjee, M. Basile, V. Borutinskaitė,G. Eissner, A. Gellhaus, B. Giebel, Yong-Can Huang, A. Janev, M. E. Kreft, N Kupper, A. C. Abadía-Molina, E. G Olivares, A. Pandolfi, A. Papait, M. Pozzobon, C. Ruiz-Rui, O. Soritau, S. Susman, D. Szukiewicz, A. Weidinger, S. Wolbank, B. Huppertz, O. Parolini. 2020. Perinatal derivatives: where do we stand? A roadmap of the human placenta and consensus for tissue and cell nomenclature. Frontiers in Bioengineering and Biotechnology 8: AN 610544. IF 5,89
- Skeberdytė A, I. Sarapinienė, J.A. Krasko, A. Barakauskienė, K. Žilionytė, R. Prokarenkaitė, K. Sužiedėlis, V. Bukelskienė, S. Jarmalaitė. 2020. Salinomycin and dichloroacetate synergistically inhibit Lewis lung carcinoma cell proliferation, tumor growth and metastasis. Biochemical and Biophysical Research Communications 523:874-879 IF 3.575
- Stanislauskienė R., A. Laurynėnas, R. Rutkienė, A. Aučynaitė, D. Tauraitė, R. Meškienė, N. Urbelienė, A. Kaupinis, M. Valius, L. Kalinienė, R. Meškys. 2020. YqfB protein from Escherichia coli: an atypical amidohydrolase active towards N4-acylcytosine derivatives. Scientific Reports 10:788. IF 4.379
- Stankevič J., A. Audickaitė, S. Silovė, V. Simčikas, H. Cesiulis, G. Skujienė, V. Bukelskienė, V. Zalgevičienė, J. Tutkuvienė. 2020. Effect of ionised (electrolysed) water on the rat embryo development. Journal of Environmental Engineering and Landscape Management. 28: 28-35. IF 1.373.
- Šimoliūnienė M., L. Truncaitė, E. Petrauskaitė, A. Zajančkauskaitė, R. Meškys, M. Skapas, A. Kaupinis, M. Valius, E. Šimoliūnas. 2020. Pantoea agglomerans-infecting bacteriophage vB_PagS_AAS21: a cold-adapted virus representing a novel genus within the family Siphoviridae. Viruses 12: 479. IF 5.048
- Šimoliūnienė M., D. Tumėnas, K. Kvederavičiūtė, R. Meškys, S. Šulčius, E. Šimoliūnas. 2020. Complete genome sequence of Bacillus cereus bacteriophage vB_BceS_KLEB30-3S. Microbiology Resource Announcements 9: AN e00348-20
- Talaikis M., S. Strazdaitė, M. Žiaunys, G. Niaura. 2020. Far-off resonance: multiwavelength Raman spectroscopy probing amide bands of amyloid-beta-(37-42) peptide. Molecules 25: AN 3556. IF 4.411
- Talaikis M., G. Valinčius, G. Niaura. 2020. Potential-induced structural alterations in the tethered bilayer lipid membrane- anchoring monolayers revealed by electrochemical surface-enhanced Raman spectroscopy. Journal of Physical Chemistry C 124: 19033-19045 IF 4,126
- Truncaitė L., M. Šimoliūnienė, L. Alijošius, E. Petrauskaitė, L. Kiaušaitė, R. Meškys, M. Skapas, E. Šimoliūnas. 2020. Complete genome analysis of Pantoea agglomerans-infecting bacteriophage vB_PagM_AAM22. Archives of Virology 165(9): 2111-2114. IF 2.574
- Tumėnas S., T. Ragaliauskas, T. Penkauskas, A. Valančiūtė, F. Ambrulevičius, G. Valinčius. 2020. Solvent effects on composition and structure of thiolipid molecular anchors for tethering phospholipid bilayers. Applied Surface Science 509: AN 145268 IF 6,707
- Urbelienė N., R. Meškienė, M. Tiškus, R. Stanislauskienė, A. Aučynaitė, A. Laurynėnas, R. Meškys. 2020. A rapid method for the selection of amidohydrolases from metagenomic libraries by applying synthetic nucleosides and a uridine auxotrophic host. Catalysts 10: 445. IF 4.146
- Vaitekūnas J., R. Gasparavičiūtė, J. Stankevičiūtė, G. Urbelis, R. Meškys. 2020. Biochemical and genetic analysis of 4-hydroxypyridine catabolism in Arthrobacter sp. strain IN13. Microorganisms 8: 888. IF 4.128
- Valiauga B., N. Rouhier, J.-P. Jacquot, N. Čėnas. 2020. Characterization of redox properties of FAD cofactor of Thermotoga maritima thioredoxin reductase. Chemija 31: 191-195. IF 0,635
- Valiulienė G., A. Vitkevičienė, R. Navakauskienė. 2020. The epigenetic treatment remodel genome-wide histone H4 hyper-acetylation patterns and affect signaling pathways in acute promyelocytic leukemia cells. European Journal of Pharmacology 889: 173641 IF 4.432
- Voitechovič E., A. Vektarienė, G. Vektaris, R. Jančienė, J. Razumienė, V. Gurevičienė.2020. 1,4-Benzoquinone derivatives for enhanced bioelectrocatalysis by fructose dehydrogenase from gluconobacter japonicus: towards promising D-fructose biosensor development. Electroanalysis 32: 1005-1016 IF 3.223
- Zaleskis G., S. Garberytė, B. Pavliukevičienė, G. Valinčius, D. Characiejus, M. Mauricas, J. A. Krasko, K. Žilionytė, M. Žvirblė, V. Pašukonienė. 2020. Doxorubicin uptake in ascitic lymphoma model: resistance or curability is governed by tumor cell density and prolonged drug retention. Journal of Cancer 11: 6497-6506 IF 4.207
- Zdaniauskienė A., T. Charkova, I. Ignatjev, V. Melvydas, R. Garjonytė, I. Matulaitienė, M. Talaikis, G. Niaura. 2020. Shell-isolated nanoparticle-enhanced Raman spectroscopy for characterization of living yeast cells. Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy: 240: 118560. IF 4,098
- Zentelytė A., M. Gasiūnienė, G. Treigytė, S. Baronaitė, J. Savickienė, V. Borutinskaitė, R. Navakauskienė. 2019. Epigenetic regulation of amniotic fluid mesenchymal stem cell differentiation to the mesodermal lineages at normal and fetus-diseased gestation. Journal of Cellular Biochemistry 121: 1811-1822. IF 4.429
- Petkevičius V., J. Vaitekūnas, D. Tauraitė, J. Stankevičiūtė, D. Vaitkus, J. Šarlauskas, N. Čėnas, R. Meškys. Whole-Cell Biocatalysis Using PmlABCDEF Monooxygenase and Its Mutants: A Versatile Toolkit for Selective Synthesis of Aromatic N-Oxides. In Applied Biocatalysis: The Chemist’s Enzyme Toolbox, 528-533. Ed. J. Whittall, P. Sutton, John Wiley&Sons Ltd.
2019
- Alksnė M., E. Šimoliūnas,M. Kalvaitytė, E. Skliutas, I. Rinkūnaitė, I. Gendvilienė, D. Baltriukienė, V. Rutkūnas, V. Bukelskienė. 2019. The effect of larger than cell diameter polylactic acid surface patterns on osteogenic differentiation of rat dental pulp stem cells. Journal of Biomedical Materials Research part A 107: 174-186. IF 3.525
- Balčiūnas E., S. Baldock, N. Dreižė, M. Grubliauskaitė, S. Coultas, D.L. Rochester, M. Valius, J.G. Hardy, D. Baltriukienė. 2019. 3D printing hybrid organometallic polymer-based biomaterials via laser two-photon polymerization. Polymer International 68:1928-1940. IF 2.574
- Balčiūnas E., N. Dreižė, M. Grubliauskaitė, S. Urnikytė, E. Šimoliūnas, V. Bukelskienė, M. Valius, S. Baldock, J.G. Hardy, D. Baltriukienė. 2019. Biocompatibility investigation of hybrid organometallic polymers for sub-micron 3D printing printing via laser two-photon polymerisation. Materials 12: 3932. IF 3.057
- Baronas R., J. Kulys, L. Petkevičius. 2019. Computational modeling of batch stirred tank reactor based on spherical catalyst particles. Journal of Mathematical Chemistry 57: 327-342 IF 1.795
- Borutinskaitė V., G. Treigytė, D. Matuzevičius, V. Čeksterytė, B. Kurtinaitienė, A. Serackis, D. Navakauskas, R. Navakauskienė. 2019. Proteomic studies of honeybee- and manually-collected pollen. Zemdirbyste-Agriculture 106: 183-190. IF 0.833
- Butkus S., M. Rickus, R. Sirutkaitis, D. Paipulas, V. Sirutkaitis. 2019. Fabrication of high aspect ratio channels in fused silica using femtosecond pulses and chemical etching at different conditions. Journal of Laser Micro Nanoengineering 14: 19-24 IF 0.887
- Časaitė V., M. Sadauskas, J. Vaitekūnas, R. Gasparavičiūtė, R. Meškienė, I. Skikaitė, M. Sakalauskas, J. Jakubovska, D. Tauraitė, R. Meškys. 2019. Engineering of a chromogenic enzyme screening system based on an auxiliary indole-3-carboxylic acid monooxygenase. MicrobiologyOpen 8: e00795. IF 3,412
- Čeksterytė V., Borutinskaitė V., D. Matuzevičius, G. Treigytė, D. Navakauskas, B. Kurtinaitienė, R. Navakauskienė. 2019. Evaluation of proteome profiles of Salix spp. pollen and relationship between glucose oxidase activity and pollen content in willow honey. Baltic Forestry 25: 83-96. IF 0.772
- Ferrer M., C. Méndez-García, R. Bargiela, J. Chow, S. Alonso, A. García-Moyano, G.E.K. Bjerga, I. H. Steen, T. Schwabe, C. Blom, J. Vester, A. Weckbecker, P. Shahgaldian, C.C.C.R. de Carvalho, R. Meškys, G. Zanaroli, F.O. Glöckne, A. Fernández-Guerra, S. Thambisetty, F. de la Calle, O.V. Golyshina, M.M Yakimov, K.E. Jaeger, A.F. Yakunin, W.R. Streit, O. McMeel, J.B. Calewaert, N. Tonné, P.N. Golyshin. 2019. Decoding the ocean's microbiological secrets for marine enzyme biodiscovery. FEMS Microbiology Letters 366: fny285. IF 1.987
- Gasiulė S., N. Dreižė, A. Kaupinis, R. Ražanskas, L. Čiupas, V. Stankevičius, Ž. Kapustina, A. Laurinavičius, M. Valius, G. Vilkaitis. 2019. Molecular insights into miRNA-driven resistance to 5-fluorouracil and oxaliplatin chemotherapy: miR-23b modulates the epithelial–mesenchymal transition of colorectal cancer cells. Journal of Clinical Medicine 12: 2115. IF 3,303
- Gasiūnienė M., G. Petkus, D. Matuzevičius, D. Navakauskas, R. Navakauskienė. 2019. Angiotensin II and TGF-β1 induce alterations in human amniotic fluid-derived mesenchymal stem cells leading to cardiomyogenic differentiation initiation. International Journal of Stem Cells. 12: 251-264. IF 1.94
- Gasiūnienė M., A. Zentelytė, G. Treigytė, S. Baronaitė, J. Savickienė, A. Utkus, R. Navakauskienė. 2019. Epigenetic alterations in amniotic fluid mesenchymal stem cells derived from normal and fetus-affected gestations: a focus on myogenic and neural differentiations. Cell Biology International 43: 299-312. IF 2.571
- Gasiūnienė M., A. Zentelytė, B. Wojtas, S. Baronaitė, N. Krasovskaja, J. Savickienė, B. Gielniewski, B. Kaminska, A. Utkus, R. Navakauskienė. 2019. DNA methyltransferases inhibitors effectively induce gene expression changes suggestive of cardiomyogenic differentiation of human amniotic fluid-derived mesenchymal stem cells via chromatin remodeling. Journal of Tissue Engineering and Regenerative Medicine 13: 469-481 IF 3.078
- Gasiūnienė M., A. Zubova, A. Utkus, R. Navakauskienė. 2019. Epigenetic and metabolic alterations in human amniotic fluid stem cells induced to cardiomyogenic differentiation by DNA methyltransferases and p53 inhibitors. Journal of Cellular Biochemistry 120: 8129-8143. IF 4.237
- Gineitytė J., R. Meškys, M. Dagys, D. Ratautas. 2019. Highly efficient direct electron transfer bioanode containing glucose dehydrogenase operating in human blood. Journal of Power Sources 441: 227163 IF 8,247
- Gordeeva J., N. Morozova, N. Sierro, A. Isaev, T. Sinkunas, K. Tsvetkova, M. Matlashov, L. Truncaitė, R.D. Morgan, N. V. Ivanov, V. Siksnys, L. Zeng, K. Severinov. 2019. BREX system of Escherichia coli distinguishes self from non-self by methylation of a specific DNA site. Nucleic Acid Research. 47: 253-265. IF 11.501
- Jakubovska J., D. Tauraitė, R. Meškys. 2019. Transient N4‐acyl‐DNA protection against the cleavage by restriction endonucleases. ChemBioChem 20: 2504-2512. IF 2.576
- Jančienė R., G. Mikulskienė. 2019. The complete H-1 and C-13 NMR spectra assignments of N-(2-nitrobenzoyl)-1,5-benzodiazepin-2-one and dihydroquinazolino[3,2-alpha]benzodiazepine derivatives. Magnetic Resonance in Chemistry 57: 968-974. IF 2.035
- Kazlauskas A., A. Darinskas, R. Meškys, A. Tamašauskas, J. Urbonavičius. 2019. Isocytosine deaminase Vcz as a novel tool for the prodrug cancer therapy. BMC Cancer 19: 197. IF 3,15
- Krikštolaitytė V., J. Hamit-Eminowski, L. Abariūtė, G. Niaura, R. Meškys, T. Arnebrant, G. Lisak, T. Ruzgas. 2019. Impact of molecular linker size on physicochemical properties of assembled gold nanoparticle mono-/multi-layers and their applicability for functional binding of biomolecules. Journal of Colloid and Interface Science 543: 307-316 IF 7,489
- Kučiauskas D., N. Dreižė, M. Ger, A. Kaupinis, K. Žemaitis, V. Stankevičius, K. Sužiedėlis, J. Cicėnas, Lee M. Graves, M. Valius. Proteomic analysis of breast cancer resistance to the anticancer drug RH1 reveals the importance of cancer stem cells. Cancers 11: 972. IF 6.126
- Laurinavičius V., F. Ivanauskas, A. Neciporenko. 2019. Drug delivery mathematical modeling for pressure controlled bioreactor. Journal of Mathematical Chemistry. 57: 1973-1982. IF 1.795
- Laurynėnas A., M. Butkevičius, M. Dagys, S. Shleev, J. Kulys. 2019. Consecutive Marcus electron and proton transfer in heme peroxidase compound II-catalysed oxidation revealed by Arrhenius plot. Scientific Reports 9: AN 14092. IF 3,998
- Ledas Ž., R. Šimkus, R. Baronas. 2019. Computational modeling of self-organization of bacterial population consisting of subpopulations of active and passive cells. Journal of Biological Sciences 27: 365-381. IF 0.733
- Mačernytė L., J. Skruibis, V. Vaičaitis, R. Sirutkaitis, O. Balachninaitė. 2019. Femtosecond laser micromachining of soda-lime glass in ambient air and under various aqueous solutions. Micromachines 10: 354. IF 2.523
- Marozienė A., M. Lesanavičius, E. Davioud-Charvet, A. Aliverti, P. Grellier, J. Šarlauskas, N. Čėnas. 2019. Antiplasmodial activity of nitroaromatic compounds: correlation with their reduction potential and inhibitory action on Plasmodium falciparum glutathione reductase. Molecules 24: 4509. IF 3.267
- Nassiri I., I. Alberto, E.M. Meškytė, F. Alessandrini, Y. Ciribilli, C. Priami. 2019. Regulatory crosstalk of doxorubicin, estradiol and TNFα combined treatment in breast cancer-derived cell lines. Scientific Reports 9: AN 15172. IF 3,998
- Nemeikaitė-Čėnienė A., J. Šarlauskas, V. Jonušienė, A. Marozienė, L. Misevičienė, A.V. Yantsevich, N. Čėnas. 2019. Kinetics of flavoenzyme-catalyzed reduction of tirapazamine derivatives: implications for their prooxidant cytotoxicity. International Journal of Molecular Sciences 20: pii: E4602. IF 4.556
- Pavliukevičienė B., A. Zentelytė, M. Jankunec, G. Valiulienė, M. Talaikis, R. Navakauskienė, G. Niaura, G. Valinčius. 2019. Amyloid β oligomers inhibit growth of human cancer cells. Plos One 14(9): e0221563. IF 2,74
- Penkauskas T., G. Preta. 2019. Biological applications of tethered bilayer lipid membranes. Biochimie 157: 131-141. IF 3.413.
- Peterman E., P. Gibieza, J. Schafer, V.A. Skeberdis, A. Kaupinis, M. Valius, X. Heiligenstein, I. Hurbain, G. Raposo, R. Prekeris. 2019. The post-abscission midbody is an intracellular signaling organelle that regulates cell proliferation. Nature Communications 10: Article Number: 3181. IF 12.121
- Petkevičius V., J. Vaitekūnas, D. Tauraitė, J. Šarlauskas, N. Čėnas, R. Meškys. 2019. A biocatalytic synthesis of heteroaromatic N‐oxides by whole cells of Escherichia coli expressing the multicomponent, soluble di‐iron monooxygenase (SDIMO) PmlABCDEF. Advanced Synthesis&Catalysis 361: 2456-2465. IF 5.851
- Petkevičius V., J. Vaitekūnas, D. Vaitkus, N. Čėnas, R. Meškys. 2019. Tailoring a soluble diiron monooxygenase for synthesis of aromatic N-oxides. Catalysts 9: 356 IF 3.52
- Polmickaitė-Smirnova E., S. Bagdonas, Ž. Anusevičius. 2019. Sensitization of Salmonella enterica with 5-aminolevulinic acid-induced endogenous porphyrins: a spectroscopic study. Photochemical & Photobiological Sciences 18: 2730-2739. IF 2.831
- Ragaliauskas T., M. Plečkaitytė, M. Jankunec, L. Labanauskas, L. Baranauskienė, G. Valinčius. 2019. Inerolysin and vaginolysin, the cytolysins implicated in vaginal dysbiosis, differently impair molecular integrity of phospholipid membranes. Scientific Reports 9: AN 10606. IF 3,998.
- Raila T., T. Penkauskas, M. Jankunec, G. Dreižas, T. Meškauskas, G. Valinčius. 2019. Electrochemical impedance of randomly distributed defects in tethered phospholipid bilayers: Finite element analysis. Electrochimica Acta 299: 863-874. IF 6.215
- Ramonas E., D. Ratautas, M. Dagys, R. Meškys, J. Kulys. 2019. Highly sensitive amperometric biosensor based on alcohol dehydrogenase for determination of glycerol in human urine. Talanta 200: 333-339. IF 5.339
- Rekovič L., L. Kosychova, I. Bratkovskaja, R. Vidžiūnaitė. 2019. Synthesis and spectral characterization of novel 1,5-benzodiazepine oxime derivatives. Journal of the Serbian Chemical Society 84: 343-353. IF 1,097
- Rynkevičienė R., J. Šimienė, E. Strainienė, V. Stankevičius, J. Usinskienė, E. Mišeikytė Kaubrienė, I. Meškinytė, J. Cicėnas, K. Sužiedėlis. 2019. Non-coding RNAs in glioma. Cancers 11:17 IF 6.126
- Šarlauskas J., E. Polmickaitė-Smirnova, N. Čėnas, K. Krikštopaitis, Ž. Anusevičius. 2019. The QSAR study for antibacterial activity of structurally diverse nitroaromatics. Chemija 30: 41-48. IF 0.305
- Šimoliūnas E., I. Rinkūnaitė, Ž. Bukelskienė, V. Bukelskienė. 2019. Bioavailability ofdifferent vitamin D oral supplements in laboratory animal model. Medicina-Lithuania 55: DE265 IF 1.205
- Šimoliūnas E., L. Truncaitė, R. Rutkienė, S. Povilonienė, K. Goda, A. Kaupinis, M. Valius, R. Meškys. 2019. The robust self-assembling tubular nanostructures formed by gp053 from by gp053 from Phage vB_EcoM_FV3. Viruses 11: AN 50. IF 3.816
- Špakova A., E. Šimoliūnas, R. Batiuškaitė, S. Pajeda, R. Meškys, R. Petraitytė-Burneikienė. 2019. Self-assembly of tail tube protein of bacteriophage vB_EcoS_NBD2 into extremely long polytubes in vB_EcoS_NBD2 into Extremely Long Polytubes in E. coli and S. cerevisiae. Viruses-Basel 11: AN208. IF 3.816
- Šulčius S., E. Šimoliūnas, G. Alzbutas, G. Gasiūnas, V. Jauniškis, S. Miettinen, E. Nilsson, R. Meškys, E. Roine, R. Paškauskas, K.Holmfeldt. 2019. Genomic characterization of cyanophage vB_AphaS-CL131 infecting filamentous diazotrophic cyanobacterium Aphanizomenon flos-aquae reveals novel insights into virus-bacterium interactions. Applied and Environmental Microbiology 85: UNSP e01311-18. IF 4.016
- Talaikis M., M. Valldeperas, I. Matulaitienė, J. Borzova, J. Barauskas, G. Niaura. 2019. On the molecular interactions in lipid bilayer-water assemblies of different curvature. The Journal of Physical Chemistry B 123: 2662-2672. IF 2.857
- Umbrasas D., R. Jokubka, A. Kaupinis, M. Valius, O. Arandarčikaitė, V. Borutaitė. 2019.Nitric oxide donor NOC-18-induced changes of mitochondrial phosphoproteome in rat cardiac ischemia model. Medicina-Lithuania 55:631. IF 1.420567
- Urbelienė N., S. Kutanovas, R. Meškienė, R. Gasparavičiūtė, D. Tauraitė, M. Koplūnaitė, R. Meškys. 2019. Application of the uridine auxotrophic host and synthetic nucleosides for a rapid selection of hydrolases from metagenomic libraries. Microbial Biotechnology 12: 148-160. IF 5,328
- Vaičikauskaitė M., M. Ger, M. Valius, A. Maneikis, E. Lastauskienė, L. Kalėdienė, A. Kaunietis. 2019. Geobacillin 26 - high molecular weight bacteriocin from a thermophilic bacterium. International Journal of Biological Macromolecules 141: 333-344. IF 5,162
- Vaitkutė G., I. Bratkovskaja, V. Časaitė, J. Stankevičiūtė, R. Meškys, L. Tetianec. 2019. Electron transfer mediators for PQQ dependent soluble glucose dehydrogenase catalyzed lactose oxidation reaction. Chemija 30: 194-200. IF 0.305
- Valldeperas M., A. Salis, J. Barauskas, F. Tiberg, T. Arnebrandt, V. Razumas, M. Monduzzi, T. Nylander. 2019. Enzyme encapsulation in anostructured self-assembled structures: Toward biofunctional supramolecular assemblies. Current Opinion in Colloid&Interface Science 44: 130-142. IF 6,79
- Valldeperas M., M. Talaikis, S.K. Dhayal, M. Velicka, J. Barauskas, G. Niaura, T. Nylander. 2019. Encapsulation of aspartic protease in nonlamellar lipid liquid crystalline phases.. Biophysical Journal 117: 829-843. IF 3,854
- Vitkevičienė A., V. Janulis, A. Žučenka, V. Borutinskaitė, A. Kaupinis, M. Valius, L. Griškevičius, R. Navakauskienė. 2019. Oxidative phosphorylation inhibition induces anticancerous changes in therapy-resistant-acute myeloid leukemia patient cells. Molecular Carcinogenesis 58: 2008-2016. IF 3.825
- Vitkevičienė A., G. Skiauterytė, A. Žučenka, M. Stoškus, E. Gineikienė, V. Borutinskaitė, L. Griškevičius, R. Navakauskienė. 2019. HDAC and HMT inhibitors in combination with conventional therapy: a novel treatment option for acute promyelocytic leukemia. Journal of Oncology. Article Number: 6179573. IF 2.206
- Voitechovič E., R. Jančienė, G. Mikulskienė, A. Vektarienė, V. Vektaris, J. Razumienė. 2019. Synthesis and DFT characterisation of 2-arylamino-1,4-benzoquinone derivatives as potential electron transfer mediators. Chemija 30: 115-126. IF 0.305
Grants
International grants
European Joint Programme on Rare Diseases
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URGENT"„Unveiling the role of glutamate in dopamine transporter deficiency syndrome“ ", dr. J. Razumienė, coordinator Universite de Mons, 2020-2023
EuroNanoMed3 - European Innovative Research & Technological Development Projects in Nanomedicine
- A liquid corneaal glue-filler as an alternative to transplantation in high-risk patient (LIQD-CORNEA), dr. V. Bukelskienė, coordinator Université de Montréal, 2019-2022.
Bilateral Lithuanian-French Programme Gilibert.
Characterization of the Flavointeractome of the Antiplasmodial Agent Plasmodione and its Metabolites (No. S-LZ-19-4). Dr Habil. N. Čėnas. 2019–2021.
COST programme
- CA17116 International Network for Translating Research on Perinatal Derivatives into Therapeutic Approaches, prof. R. Navakauskienė, dr. V. Borutinskaitė, coordinator - Università Cattolica del Sacro Cuore, Roma, Italy, 2018-2022.
- A16119 In vitro 3-D total cell guidance and fitness, dr. D. Baltriukienė, Coordinator - School of Veterinary Medicine, Milan, Italy, 2016-2021.
National grants
Central Project Management Agency.
Development of Biosensor Research and Engineering Competence and Technology Transfer Centre (BIOSENSE) (No. 01.2.2-CPVA-K-703-03-0010). Dr M. Dagys. 2020–2023.
Center for Genetic Modeling of Animals, No. 01.2.2-CPVA-K-703-03-0032. Dr D. Baltriukienė. 2020–2023.
Center for Engineering of the Next-Generation Enzymes, No. 01.2.2-CPVA-K-703-03-0023. Dr R. Meškys. 2020–2023.
Lithuanian Science Programmes and Projects supported by Research Council of Lithuania
Programme „Attracting Foreign Researchers for Research Implementation“
Targeting the microbiota-gut-brain axis in Alzheimer’s disease: the role of the endocannabinoid system, dr. Aurelijus Burokas, 2019-2023.
Targeted Research in Smart Specialization Areas
Biomarkers of the Gut Microbiota in Autistic Spectrum Disorders, No. 01.2.2-LMT-K-718-01-0099. Dr A. Burokas. Partner – Center for Physical Sciences and Technology. 2020–2023.
Artificial Urethra for the Treatment of Hypospadias and Urethral Strictures, No. 01.2.2-LMT-K-718-01-0087. Dr V. Bukelskienė. Partner – Vilnius University Hospital Santaros Klinikos. 2020–2023.
Selective Enzymatic System for Prodrug Activation, No. 01.2.2-LMT-K-718-03-0082. Dr R. Meškys. 2020–2023.
Biosensor Platform for Fast, Cheap and Accurate Quantification of Amino Acids in Patients Undergoing Renal Replacement Therapy (DIALSENS) (No. 01.2.2-LMT-K-718-01-0019). Dr. D. Ratautas. Partner – Vilnius University Hospital Santaros Klinikos. 2020–2024.
Development of Non-invasive method platform for early diagnostics and prognosis of acute pancreatitis (No. 01.2.2-LMT-K-718-01-0025). Dr. Julija Razumienė. Partner – Vilnius University Hospital Santaros Klinikos. 2018 – 2022
Biocatalytic systems for conversion of non-starch poli- and oligosaccharides (No. 01.2.2-LMT-K-718-01-0019). Dr. Marius Dagys. 2018 – 2022.
“Designing of the patient-specific, heterogeneous lung cancer cell ex vivo model system for drug efficiency prediction in personalized oncotherapy”, dr. Audrone Kalvelyte, 2018 – 2022.
Global grant measure
Redox chemistry, biochemistry and cytotoxicity of aromatic nitrocompounds and N-oxides: new insighths (No. DOTSUT-34/09.33-LMT-K712-01-0058). Habil. dr. N. Čėnas. 2018-2021.
Change or die: redesign of oxidoreductases (CHORD), Dr. R. Meškys. 2013–2015.
Molecular Mechanisms of Toxicity and Antitumor Activity of Quinones and Polyphenols: Enzymatic Redox Cytotoxicity, Signal Transduction, and Proteomics. Habil. dr. N. Čėnas, 2011–2015.
Improvement of scientific qualification through individual Horizon 2020 MTEP projects
Interactions of Misfolded Proteins and Phospholipid Membranes: Possible Key in Neurodegeration (NeuroMisFolDe), No. 09.3.3-LMT-K-712-18-0003. Dr R. Budvytytė. 2020–2022.
Healthy ageing
Healthy Microbiota - Healthy Brain Aging, No. SEN-S-20-9. Dr A. Burokas. 2020–2021.
Researcher teams’ projects
Enzyme Toolkit for the Synthesis of Fucosylated Oligosaccharides, No. 01.2.2-LMT-K-718-03-0045. Dr J. Stankevičiūtė. 2020–2023.
Supramolecular recognition-based sensors for electro- detection of biomolecules. Dr. Gintautas Bagdžiūnas, 2020-2022.
Diversity and distribution of viruses infecting sulfur metabolising bacteria. Dr. Eugenijus Šimoliūnas, 2020-2022.
Molecular mechanisms of adaptation of low-temperature phages to the mesophilic host. Dr. Laura Kaliniene, 2019-2022.
Phage Proteins for Targeted Nanomedicine, No. P-SEN-20-34. Dr V. Časaitė. 2020–2021.
The EUREKA Network Application
E!13638 Innova-Fertility project Advanced Technologies for Innovative Infertility Treatment,No. 01.2.2-MITA-K-702-12-0004. Prof. Rūta Navakauskienė. 2021–2023.